BIOMAT Database Logo BIOMAT Database Logo

Adipose tissue, longissimus muscle and anterior pituitary growth and function in clenbuterol-fed heifers. 1988

M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Dept. of Anim. Sci., Texas A&M University, College Station 77843.

The present study was conducted to determine the effects of feeding clenbuterol on adipose tissue and longissimus muscle growth in heifers. For 50 d, 14 heifers were fed either a sucrose-based, clenbuterol supplement or a placebo in which the clenbuterol had been omitted. The heifers were slaughtered in two groups, based on initial weight. Adipose tissue from several anatomical sites and longissimus muscle (depending on slaughter group) were obtained fresh at slaughter. Changes in carcass characteristics elicited by clenbuterol were similar to those reported by others for steers and sheep. Subcutaneous (sc) and intramuscular (im), but not perirenal, adipocytes were smaller and there were more cells per g tissue in the adipose tissue depots of the clenbuterol-fed heifers. Clenbuterol decreased lipogenic enzyme activities, fatty acid-binding protein activity, basal lipolysis and acetate incorporation into glyceride-fatty acids (P less than .05) in sc adipose tissue, but had no effect (P greater than .05) on lipogenesis or lipolysis in im adipose tissue. Clenbuterol elicited a 20% increase in type II myofiber diameters (P less than .05) but had no effect on type I myofiber diameters. In vitro growth hormone release by perifused anterior pituitaries was not affected significantly by long-term in vivo exposure to clenbuterol. These data indicate that a depression in lipogenesis is the mechanism by which clenbuterol decreases subcutaneous fat accretion in cattle.

UI MeSH Term Description Entries
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D010903 Pituitary Gland, Anterior The anterior glandular lobe of the pituitary gland, also known as the adenohypophysis. It secretes the ADENOHYPOPHYSEAL HORMONES that regulate vital functions such as GROWTH; METABOLISM; and REPRODUCTION. Adenohypophysis,Anterior Lobe of Pituitary,Anterior Pituitary Gland,Lobus Anterior,Pars Distalis of Pituitary,Adenohypophyses,Anterior Pituitary Glands,Anterior, Lobus,Anteriors, Lobus,Lobus Anteriors,Pituitary Anterior Lobe,Pituitary Glands, Anterior,Pituitary Pars Distalis
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002976 Clenbuterol A substituted phenylaminoethanol that has beta-2 adrenomimetic properties at very low doses. It is used as a bronchodilator in asthma. NAB-365,Planipart,NAB 365,NAB365
D004983 Ethanolamines AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives. Aminoethanols
D005260 Female Females
D000273 Adipose Tissue Specialized connective tissue composed of fat cells (ADIPOCYTES). It is the site of stored FATS, usually in the form of TRIGLYCERIDES. In mammals, there are two types of adipose tissue, the WHITE FAT and the BROWN FAT. Their relative distributions vary in different species with most adipose tissue being white. Fatty Tissue,Body Fat,Fat Pad,Fat Pads,Pad, Fat,Pads, Fat,Tissue, Adipose,Tissue, Fatty
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D024510 Muscle Development Developmental events leading to the formation of adult muscular system, which includes differentiation of the various types of muscle cell precursors, migration of myoblasts, activation of myogenesis and development of muscle anchorage. Myofibrillogenesis,Myogenesis,Muscular Development,Development, Muscle,Development, Muscular

Related Publications

M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Adipose tissue cellularity and muscle growth in young steers fed the beta-adrenergic agonist clenbuterol for 50 days and after 78 days of withdrawal.
November 1990, Journal of animal science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Changes in colour characteristics and pigmentation of subcutaneous adipose tissue and M. longissimus dorsi of heifers fed grass, grass silage or concentrate-based diets.
October 2006, Meat science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Partitioning variances of growth in ultrasound longissimus muscle area measures in Angus bulls and heifers.
May 2004, Journal of animal science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Anterior pituitary gland and lymphoid tissue growth.
January 1958, Acta endocrinologica. Supplementum,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Protein turnover and growth of L8 muscle cultures in serum from rats fed clenbuterol.
January 1988, Growth, development, and aging : GDA,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Transcript profiles in longissimus dorsi muscle and subcutaneous adipose tissue: a comparison of pigs with different postweaning growth rates.
May 2015, Journal of animal science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Effects of genetic markers and implant strategy on longissimus and gluteus muscle tenderness of calf-fed steers and heifers.
May 2011, Journal of animal science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Growth, carcass characteristics, and lipid composition of adipose tissue and muscle of pigs fed canola.
March 1991, Journal of animal science,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
Longissimus muscle growth in swine.
December 1969, Growth,
M F Miller, and D K Garcia, and M E Coleman, and P A Ekeren, and D K Lunt, and K A Wagner, and M Procknor, and T H Welsh, and S B Smith
RNA-seq analysis of bovine adipose tissue in heifers fed diets differing in energy and protein content.
January 2018, PloS one,
Copied contents to your clipboard!