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Real-life use of remdesivir in hospitalized patients with COVID-19. 2021
C Garcia-Vidal, and
F Meira, and
A Cózar-Llistó, and
G Dueñas, and
P Puerta-Alcalde, and
N Garcia-Pouton, and
M Chumbita, and
C Cardozo, and
M Hernandez-Meneses, and
R Alonso-Navarro, and
V Rico, and
D Agüero, and
M Bodro, and
L Morata, and
C Jordan, and
C Lopera, and
J Ambrosioni, and
F Segui, and
N Grafia, and
P Castro, and
F García, and
J Mensa, and
J A Martínez, and
G Sanjuan, and
A Soriano, and
OBJECTIVE Controversial results on remdesivir efficacy have been reported. We aimed to report our real-life experience with the use of remdesivir from its availability in Spain. METHODS We performed a descriptive study of all patients admitted for ≥48 hours with confirmed COVID-19 who received remdesivir between the 1st of July and the 30th of September 2020. RESULTS A total of 123 patients out of 242 admitted with COVID-19 at our hospital (50.8%) received remdesivir. Median age was 58 years, 61% were males and 56.9 % received at least one anti-inflammatory treatment. No adverse events requiring remdesivir discontinuation were reported. The need of intensive care unit admission, mechanical ventilation and 30-days mortality were 19.5%, 7.3% and 4.1%, respectively. CONCLUSIONS In our real-life experience, the use of remdesivir in hospitalized patients with COVID-19 was associated with a low mortality rate and good safety profile.
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American family physician,
