Triggered activity as a mechanism of recurrent ventricular tachycardia. 1988

A K Bhandari, and R A Hong, and S H Rahimtoola
Department of Medicine, LAC-USC Medical Center, University of Southern California School of Medicine 90033.

Triggered activity was shown to be the likely mechanism of recurrent tachycardia in a 28 year old Vietnamese man. During baseline electrophysiological testing the tachycardia was induced consistently by prolonged atrial or ventricular pacing but not by premature extrastimuli. Moreover, the tachycardia coupling intervals varied directly with the cycle length of the initiating drive. Procainamide and propranolol did not suppress tachycardia, but verapamil terminated it and prevented its reinitiation. The origin of the tachycardia was localised to the left ventricular inferoapical segment and four direct current countershocks of 200 J each delivered via an electrode catheter abolished the tachycardia. During 12 months of follow up the patient was not treated with antiarrhythmic agents and the tachycardia did not recur.

UI MeSH Term Description Entries
D008297 Male Males
D012008 Recurrence The return of a sign, symptom, or disease after a remission. Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D002304 Cardiac Pacing, Artificial Regulation of the rate of contraction of the heart muscles by an artificial pacemaker. Pacing, Cardiac, Artificial,Artificial Cardiac Pacing,Artificial Cardiac Pacings,Cardiac Pacings, Artificial,Pacing, Artificial Cardiac,Pacings, Artificial Cardiac
D004554 Electric Countershock An electrical current applied to the HEART to terminate a CARDIAC ARRHYTHMIA. Cardiac Electroversion,Cardioversion,Defibrillation, Electric,Electroversion, Cardiac,Electrical Cardioversion,Electroversion Therapy,Therapy, Electroversion,Cardiac Electroversions,Cardioversion, Electrical,Cardioversions,Cardioversions, Electrical,Countershock, Electric,Countershocks, Electric,Defibrillations, Electric,Electric Countershocks,Electric Defibrillation,Electric Defibrillations,Electrical Cardioversions,Electroversion Therapies,Electroversions, Cardiac,Therapies, Electroversion
D006329 Heart Conduction System An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart. Conduction System, Heart,Conduction Systems, Heart,Heart Conduction Systems,System, Heart Conduction,Systems, Heart Conduction
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013610 Tachycardia Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia. Tachyarrhythmia,Tachyarrhythmias,Tachycardias

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