-transparent.png){kind=logo}
We report the clinical and pathologic findings in a 22-year-old woman with XY gonadal dysgenesis (Swyer's syndrome), who had bilateral gonadoblastoma associated on the right side with a dysgerminoma and an embryonal carcinoma. Swyer's syndrome is a distinct type of pure gonadal dysgenesis characterized by a 46 XY karyotype. It shows an abnormality in testicular differentiation. The patients are phenotypic females without stigmas of Turner syndrome. They have also elevated gonadotropins and hypoplastic gonads without germ-cells. The tumor that usually develops in Swyer's syndrome is gonadoblastoma. This tumor arises on dysgenesic gonads with a Y chromosome. Although gonadoblastoma is considered benign, the risk of malignant germ cell development is high. This means that these dysgenesic gonads should be removed surgically as soon as Swyer's syndrome is established.
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
July 2008,
La Tunisie medicale,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
June 1990,
Gynecologic oncology,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
February 1989,
Gynecologic oncology,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
November 1989,
Nihon Sanka Fujinka Gakkai zasshi,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
October 1993,
Journal of Korean medical science,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
October 1982,
Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
September 1984,
Southern medical journal,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
December 1991,
Changgeng yi xue za zhi,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
July 2020,
BMJ case reports,
K Ben Romdhane, and
A Bessrour, and
M S Ben Amor, and
M Ben Ayed
November 2010,
Orvosi hetilap,
