Effect of marathon training on the plasma lactate response to submaximal exercise in middle-aged men. 1988

A G Rumley, and R Taylor, and S Grant, and A R Pettigrew, and I Findlay, and H Dargie
Department of Pathological Biochemistry, Western Infirmary, Glasgow.

Twenty-one previously sedentary male volunteers (aged 35-50 years) undertook a defined marathon training programme lasting 30 weeks. At weeks 0 (T1), 15 (T2) and 30 (T3) they underwent measurement of maximal oxygen uptake (VO2 max), submaximal VO2 and submaximal plasma lactate concentration during cycle ergometry. No exercise was taken for 24-48 hours prior to testing. During training aerobic power increased significantly (p less than 0.001) from an initial VO2 max at T1 of 33.9 +/- 6 (mean +/- sd) ml.kg-1min-1 to 39 +/- 5.6 ml.kg-1min-1 at T2 but the T3 value of 39.2 +/- 5.2 ml.kg-1min-1 was not significantly different from that at T2. Plasma lactate concentration of 4 mmol.l-1 (OBLAw) occurred at a significantly (P less than 0.05) higher workload (155 +/- 28 w) at T2 compared with T1 (132 +/- 30 w) but the T3 figure was 137 +/- 34 w. OBLA VO2 at T1 was 2.04 +/- 0.42 l.min-1, at T2 was 2.24 +/- 0.04 l.min-1 but at T3 was 2.03 +/- 0.30 l.min-1 (T1:T2 P less than 0.05, T1:T3 NS). OBLA % VO2 max at T1 was 75 +/- 12%, at T2 was 73 +/- 11% but at T3 was 62 +/- 10% (T1:T2 NS, T1:T3 P less than 0.01).

UI MeSH Term Description Entries
D007773 Lactates Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010101 Oxygen Consumption The rate at which oxygen is used by a tissue; microliters of oxygen STPD used per milligram of tissue per hour; the rate at which oxygen enters the blood from alveolar gas, equal in the steady state to the consumption of oxygen by tissue metabolism throughout the body. (Stedman, 25th ed, p346) Consumption, Oxygen,Consumptions, Oxygen,Oxygen Consumptions
D010806 Physical Education and Training Instructional programs in the care and development of the body, often in schools. The concept does not include prescribed exercises, which is EXERCISE THERAPY. Education, Physical,Physical Education,Physical Education, Training
D005082 Physical Exertion Expenditure of energy during PHYSICAL ACTIVITY. Intensity of exertion may be measured by rate of OXYGEN CONSUMPTION; HEAT produced, or HEART RATE. Perceived exertion, a psychological measure of exertion, is included. Physical Effort,Effort, Physical,Efforts, Physical,Exertion, Physical,Exertions, Physical,Physical Efforts,Physical Exertions
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012420 Running An activity in which the body is propelled by moving the legs rapidly. Running is performed at a moderate to rapid pace and should be differentiated from JOGGING, which is performed at a much slower pace. Runnings
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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