Biomaterial Database

Molecular Biology of Bacillus subtilis Cytochromes anno 2020. 2021

Lars Hederstedt

The Microbiology Group, Department of Biology, Lund University, Lund, 22362, Sweden. Lars.Hederstedt@biol.lu.se.

Bacillus subtilis serves as a model Gram-positive bacterium and an experimental system for research on respiratory enzymes. This review presents the heme proteins currently known for the well-characterized laboratory strain B. subtilis 168. It focuses on advances in research made during the last three decades concerning the function and composition of the cytochrome bc complex, terminal oxidases, and succinate:menaquinone oxidoreductase. The aerobic respiratory system of strain 168 seems representative for the species B. subtilis, as determined by the cytochrome composition of the undomesticated strain B. subtilis NCIB 3610 and a set of constructed cytochrome-deficient mutants of this strain. Unexplained and unsettled aspects of the molecular biology of respiratory cytochromes in B. subtilis are highlighted in the review.

UI	MeSH Term	Description	Entries
D003580	Cytochromes	Hemeproteins whose characteristic mode of action involves transfer of reducing equivalents which are associated with a reversible change in oxidation state of the prosthetic group. Formally, this redox change involves a single-electron, reversible equilibrium between the Fe(II) and Fe(III) states of the central iron atom (From Enzyme Nomenclature, 1992, p539). The various cytochrome subclasses are organized by the type of HEME and by the wavelength range of their reduced alpha-absorption bands.	Cytochrome
D004579	Electron Transport	The process by which ELECTRONS are transported from a reduced substrate to molecular OXYGEN. (From Bennington, Saunders Dictionary and Encyclopedia of Laboratory Medicine and Technology, 1984, p270)	Respiratory Chain,Chain, Respiratory,Chains, Respiratory,Respiratory Chains,Transport, Electron
D001412	Bacillus subtilis	A species of gram-positive bacteria that is a common soil and water saprophyte.	Natto Bacteria,Bacillus subtilis (natto),Bacillus subtilis subsp. natto,Bacillus subtilis var. natto
D001426	Bacterial Proteins	Proteins found in any species of bacterium.	Bacterial Gene Products,Bacterial Gene Proteins,Gene Products, Bacterial,Bacterial Gene Product,Bacterial Gene Protein,Bacterial Protein,Gene Product, Bacterial,Gene Protein, Bacterial,Gene Proteins, Bacterial,Protein, Bacterial,Proteins, Bacterial