Very long-term follow-up of autologous pubovaginal fascia slings in women with stress urinary incontinence. 2022

Sandy Kim, and Daniel G Wong, and Dominic Lee, and Alana L Christie, and Philippe E Zimmern
Department of Urology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9110, USA.

The objective was to report on the very long-term outcome of a published series of autologous pubovaginal slings (PVS) in women with stress urinary incontinence (SUI). Following institutional review board approval, a cohort of well characterized, non-neurogenic women who underwent an autologous PVS (primary [PVS1] and secondary [PVS2]) for SUI was re-evaluated for their very long-term outcome status. Data collected included demographics, validated questionnaires (Urogenital Distress Inventory - short form [UDI-6], Incontinence Impact Questionnaire - short form 7, quality of life), SUI retreatment/operations, and subjective patient-reported SUI improvement (%) and symptom recurrence. The primary outcome was success defined as UDI-6 question 3 (SUI) ≤ 1 and no SUI retreatment/operation. Patients not seen in clinic for 2 years were contacted via a standardized phone interview. From 83 patients with 7-year intermediate follow-up data, 34 (PVS1 = 18, PVS2 = 16) had very long-term follow-up based on clinic visit (7) or phone interviews (27). Those lost to follow-up (49), including 5 deceased, did not differ in demographics and intermediate outcomes from the followed cohort, but lived further away (>75 miles). At a mean age of 74 years, and with a median follow-up of 14.5 years, 53% met the success criteria (PVS1 = 44%, PVS2 = 63%). Mean postoperative questionnaire scores did not differ significantly between intermediate and very long-term follow-ups, and long-term outcomes between PVS1 and PVS2 remained similar. A majority of women with long-term follow-up after PVS for primary and secondary SUI remained successful more than 14 years after their surgery. Both groups, PVS1 and PVS2, fared equally well, confirming the durability of PVS as a treatment alternative for SUI.

UI MeSH Term Description Entries
D008297 Male Males
D011788 Quality of Life A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease. HRQOL,Health-Related Quality Of Life,Life Quality,Health Related Quality Of Life
D005205 Fascia Layers of connective tissue of variable thickness. The superficial fascia is found immediately below the skin; the deep fascia invests MUSCLES, nerves, and other organs.
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D014550 Urinary Incontinence, Stress Involuntary discharge of URINE as a result of physical activities that increase abdominal pressure on the URINARY BLADDER without detrusor contraction or overdistended bladder. The subtypes are classified by the degree of leakage, descent and opening of the bladder neck and URETHRA without bladder contraction, and sphincter deficiency. Urinary Stress Incontinence,Incontinence, Urinary Stress,Stress Incontinence, Urinary
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D053825 Suburethral Slings Support structures, made from natural or synthetic materials, that are implanted below the URETHRA to treat URINARY STRESS INCONTINENCE. Male Slings,Male Urethral Slings,Mid-Urethral Slings,Midurethral Slings,Tension-Free Vaginal Tape,Tensionless Vaginal Tape,Trans-Obturator Tape,Transobturator Suburethral Tape,Transobturator Tape,Urethral Slings,Male Sling,Male Urethral Sling,Mid Urethral Slings,Mid-Urethral Sling,Midurethral Sling,Sling, Male,Sling, Male Urethral,Sling, Mid-Urethral,Sling, Midurethral,Sling, Suburethral,Sling, Urethral,Slings, Male,Slings, Male Urethral,Slings, Mid-Urethral,Slings, Midurethral,Slings, Suburethral,Slings, Urethral,Suburethral Sling,Suburethral Tape, Transobturator,Suburethral Tapes, Transobturator,Tape, Tension-Free Vaginal,Tape, Tensionless Vaginal,Tape, Trans-Obturator,Tape, Transobturator,Tape, Transobturator Suburethral,Tapes, Tension-Free Vaginal,Tapes, Tensionless Vaginal,Tapes, Trans-Obturator,Tapes, Transobturator,Tapes, Transobturator Suburethral,Tension Free Vaginal Tape,Tension-Free Vaginal Tapes,Tensionless Vaginal Tapes,Trans Obturator Tape,Trans-Obturator Tapes,Transobturator Suburethral Tapes,Transobturator Tapes,Urethral Sling,Urethral Sling, Male,Urethral Slings, Male,Vaginal Tape, Tension-Free,Vaginal Tape, Tensionless,Vaginal Tapes, Tension-Free,Vaginal Tapes, Tensionless

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