Infective endocarditis (IE) is an inflammatory process caused by the implantation of bacteria on the heart valves or wall insertion. Bacteria leading to IE may be caused by oral procedures, such as tooth extractions, periodontal treatments, root canal treatment, scaling and tooth implantation. Antibiotic prophylaxis should only be used in accordance with the recommendations in the high-risk group of IEs, by providing the appropriate antibiotic 30-60 min. Before the planned dental treatment. In addition to appropriate antibiotic prophylaxis, special emphasis should be placed on improving dental care, regular check-ups and planned dental treatment as well as on maintaining proper oral hygiene.