The Thermal Damage of Canine Vocal Fold by CO2 Laser Under Different Laser Emission Mode. 2022

Xumao Li, and Jiaying Li, and Xidong Cui, and Xinqi Hu, and Pengcheng Yu, and Guangbin Sun
Department of Otorhinolaryngology-Head and Neck Surgery, 159397Huashan Hospital, Fudan University, Shanghai, People's Republic of China.

OBJECTIVE The purpose of this study is to review the differences between continuous wave (CW) and UltraPulse (UP) on thermal damage of the laser with different power. METHODS Four adult beagle dogs underwent transoral laser microsurgery (TLM) using CO2 laser. The laser emission mode and power was CW (3 W, 5 W, and 8 W) and UP (3 W and 5 W), respectively. The tissue from 4 animals was evaluated histologically on postoperative days 1 and 3. The thermal damage of the laser was measured using slide scan system via SlideViewer version 1.5.5.2 software. RESULTS All dogs underwent TLM uneventfully. Under microscope examined, the laser damage area was composed of 2 parts: the vaporized zone (VPZ) and thermal damage area. The thermal damage area can be divided into thermal coagulative necrosis area (TCN) and hydropic degeneration area. The width of VPZ and TCN in UP mode was less than that in CW mode (P < .01). The data indicate that lower laser power created less thermal damage (P < .01). In addition, the width of VPZ on postoperative day 3 was less than that on postoperative day 1 (P < .01). CONCLUSIONS CO2 laser with UP and lower power could decrease the laser thermal damage and may offer more prompt wound healing.

UI MeSH Term Description Entries
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014827 Vocal Cords A pair of cone-shaped elastic mucous membrane projecting from the laryngeal wall and forming a narrow slit between them. Each contains a thickened free edge (vocal ligament) extending from the THYROID CARTILAGE to the ARYTENOID CARTILAGE, and a VOCAL MUSCLE that shortens or relaxes the vocal cord to control sound production. Vocal Fold,Vocal Folds,Vocal Ligament,Cord, Vocal,Cords, Vocal,Fold, Vocal,Folds, Vocal,Ligament, Vocal,Ligaments, Vocal,Vocal Cord,Vocal Ligaments
D014945 Wound Healing Restoration of integrity to traumatized tissue. Healing, Wound,Healings, Wound,Wound Healings
D053685 Laser Therapy The use of photothermal effects of LASERS to coagulate, incise, vaporize, resect, dissect, or resurface tissue. Laser Knife,Laser Scalpel,Surgery, Laser,Vaporization, Laser,Laser Ablation,Laser Knives,Laser Photoablation of Tissue,Laser Surgery,Laser Tissue Ablation,Nonablative Laser Treatment,Pulsed Laser Tissue Ablation,Ablation, Laser,Ablation, Laser Tissue,Knife, Laser,Knifes, Laser,Knive, Laser,Knives, Laser,Laser Knifes,Laser Knive,Laser Scalpels,Laser Surgeries,Laser Therapies,Laser Treatment, Nonablative,Laser Treatments, Nonablative,Laser Vaporization,Nonablative Laser Treatments,Scalpel, Laser,Scalpels, Laser,Surgeries, Laser,Therapies, Laser,Therapy, Laser,Tissue Ablation, Laser
D054020 Lasers, Gas Lasers in which a gas lasing medium is stimulated to emit light by an electric current or high-frequency oscillator. Argon Ion Lasers,CO2 Lasers,Carbon Dioxide Lasers,Copper Vapor Lasers,Gas Lasers,Gold Vapor Lasers,Helium Lasers,Helium Neon Gas Lasers,Metal Vapor Lasers,Nitrogen Lasers,Xenon Ion Lasers,HeNe Lasers,Lasers, Argon Ion,Lasers, CO2,Lasers, Carbon Dioxide,Lasers, Copper Vapor,Lasers, Gold Vapor,Lasers, Helium,Lasers, Helium Neon Gas,Lasers, Metal Vapor,Lasers, Nitrogen,Lasers, Xenon Ion,Argon Ion Laser,CO2 Laser,Carbon Dioxide Laser,Copper Vapor Laser,Dioxide Laser, Carbon,Dioxide Lasers, Carbon,Gas Laser,Gold Vapor Laser,HeNe Laser,Helium Laser,Ion Laser, Argon,Ion Laser, Xenon,Ion Lasers, Argon,Ion Lasers, Xenon,Laser, Argon Ion,Laser, CO2,Laser, Carbon Dioxide,Laser, Copper Vapor,Laser, Gas,Laser, Gold Vapor,Laser, HeNe,Laser, Helium,Laser, Metal Vapor,Laser, Nitrogen,Laser, Xenon Ion,Lasers, HeNe,Metal Vapor Laser,Nitrogen Laser,Vapor Laser, Copper,Vapor Laser, Gold,Vapor Laser, Metal,Vapor Lasers, Copper,Vapor Lasers, Gold,Vapor Lasers, Metal,Xenon Ion Laser

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