[Oxylipins - biologically active substances of food]. 2021

A D Kupina, and Yu A Petrov
Rostov State Medical University of the Ministry of Healthcare of the Russian Federation, 344022, Rostov-on-Don, Russian Federation.

Vitamin D with its steroid structure is currently considered as a hormone. New target cells of this hormone have been identified, including those in the organs of the reproductive system. The aim - to analyze modern sources of domestic and foreign scientific literature covering the role of vitamin D in the reproductive health of women of different ages. Results. The Russian Federation is endemic in terms of vitamin D deficiency. According to statistics, a lack of this vitamin is observed in 70-90% of the population of the USA and European countries, which brings this problem to the international level. It has been established that vitamin D affects not only bone-mineral homeostasis, but also many organs and tissues, including the reproductive system, namely the ovaries, uterus, placental tissue, pituitary gland and male reproductive organs. Studies have proven the positive effect of this hormone on the course of polycystic ovary syndrome, endometriosis, diabetes mellitus (including gestational). In addition, it has been shown that vitamin D is an important micronutrient during pregravid preparation, and the normalization of its level can improve the quality and increase the life expectancy of women after 50-60 years. Conclusion. Vitamin D plays an important role in many physiological processes, including the effects on the organs of the reproductive system. The significant influence of this vitamin can be traced from the beginning of intrauterine development to the end of life, which makes its further study an important area of modern medicine, including within the framework of obstetrics and gynecology.

UI MeSH Term Description Entries
D008297 Male Males
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011085 Polycystic Ovary Syndrome A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading. Stein-Leventhal Syndrome,Polycystic Ovarian Syndrome,Polycystic Ovary Syndrome 1,Sclerocystic Ovarian Degeneration,Sclerocystic Ovaries,Sclerocystic Ovary Syndrome,Ovarian Degeneration, Sclerocystic,Ovarian Syndrome, Polycystic,Ovary Syndrome, Polycystic,Ovary, Sclerocystic,Sclerocystic Ovary,Stein Leventhal Syndrome,Syndrome, Polycystic Ovary,Syndrome, Stein-Leventhal
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014807 Vitamin D A vitamin that includes both CHOLECALCIFEROLS and ERGOCALCIFEROLS, which have the common effect of preventing or curing RICKETS in animals. It can also be viewed as a hormone since it can be formed in SKIN by action of ULTRAVIOLET RAYS upon the precursors, 7-dehydrocholesterol and ERGOSTEROL, and acts on VITAMIN D RECEPTORS to regulate CALCIUM in opposition to PARATHYROID HORMONE.
D014808 Vitamin D Deficiency A nutritional condition produced by a deficiency of VITAMIN D in the diet, insufficient production of vitamin D in the skin, inadequate absorption of vitamin D from the diet, or abnormal conversion of vitamin D to its bioactive metabolites. It is manifested clinically as RICKETS in children and OSTEOMALACIA in adults. (From Cecil Textbook of Medicine, 19th ed, p1406) Deficiency, Vitamin D,Deficiencies, Vitamin D,Vitamin D Deficiencies
D054883 Oxylipins Eighteen-carbon cyclopentyl polyunsaturated fatty acids derived from ALPHA-LINOLENIC ACID via an oxidative pathway analogous to the EICOSANOIDS in animals. Biosynthesis is inhibited by SALICYLATES. A key member, jasmonic acid of PLANTS, plays a similar role to ARACHIDONIC ACID in animals. Oxylipin

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