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Advanced strategies for development of vaccines against human bacterial pathogens. 2021
Abhinay Sharma, and
Pooja Sanduja, and
Aparna Anand, and
Pooja Mahajan, and
Carlos A Guzman, and
Puja Yadav, and
Amit Awasthi, and
Emanuel Hanski, and
Meenakshi Dua, and
Atul Kumar Johri
School of Life Sciences, Jawaharlal Nehru University, Aruna Asaf Ali Marg, New Delhi, 110067, India.
Infectious diseases are one of the main grounds of death and disabilities in human beings globally. Lack of effective treatment and immunization for many deadly infectious diseases and emerging drug resistance in pathogens underlines the need to either develop new vaccines or sufficiently improve the effectiveness of currently available drugs and vaccines. In this review, we discuss the application of advanced tools like bioinformatics, genomics, proteomics and associated techniques for a rational vaccine design.
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