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Oncogenic transformation was assayed after C3H 10T1/2 cells were irradiated with monoenergetic neutrons; cells were exposed to 0.23-, 0.35-, 0.45-, 5.9-, and 13.7-MeV neutrons given singly or in five equal fractions over 8 h. At the biologically effective neutron energy of 0.45 MeV, enhancement of transformation was evident with some small fractionated doses (below 1 Gy). When transformation was examined as a function of neutron energy at 0.5 Gy, enhancement was seen for cells exposed to three of the five energies (0.35, 0.45, and 5.9 MeV). Enhancement was greatest for cells irradiated with 5.9-MeV neutrons. Of the neutron energies examined, 5.9-MeV neutrons had the lowest dose-averaged lineal energy and linear energy transfer. This suggests that enhancement of transformation by fractionated low doses of neutrons may be radiation-quality dependent.
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
February 1989,
Radiation research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
May 1994,
Radiation research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
January 1979,
Cancer research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
October 1983,
International journal of radiation biology and related studies in physics, chemistry, and medicine,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
June 1985,
Radiation research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
April 1974,
European journal of cancer,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
May 1974,
European journal of cancer,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
March 1991,
Radiation research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
October 1991,
Radiation research,
R C Miller, and
D J Brenner, and
C R Geard, and
K Komatsu, and
S A Marino, and
E J Hall
July 1983,
Radiation research,
