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Monoclonal antibodies have been raised against cytotrophoblast. Two different antigens, defined on cytotrophoblast but not on syncytiotrophoblast were designated ACT-1 and ACT-2, respectively. Chorionic villi were taken from normal early pregnancy and processed for immunization by two different procedures. ACT-1 was demonstrated to be present in lung alveolar cells, endothelial mucosa of the jejunum, colon, ureter, urinary bladder and the fallopian tube, and endometrial gland of the pregnant uterus. On the other hand, ACT-2 was present in the endothelial mucosa of the stomach, endothelium of the renal vessel, and the decidua of the pregnant uterus. Although the monoclonal antibodies did not react with such established cell lines as Bewo, SCH, OVK-18, HHUA, MK-01, FL, BHK and P3 X 63Ag 8 . 653, they did react with some of the cell lines when the cell membrane was destroyed with Triton X-100. Each antibody, therefore, may recognize the antigen not on the cell membrane but in the cytoplasm. The antigens might be shed or may disappear in the process of differentiation from cytotrophoblast to syncytiotrophoblast.
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
January 1984,
Critical reviews in immunology,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
January 1986,
Cancer research,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
August 1981,
Proceedings of the National Academy of Sciences of the United States of America,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
January 1981,
Immunological reviews,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
January 1986,
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
November 1984,
Brain research,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
February 1982,
Proceedings of the National Academy of Sciences of the United States of America,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
February 1982,
Cancer research,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
February 1984,
Cancer research,
Y Abe, and
K Okamura, and
Y Hamazaki, and
Y Wada, and
A Yajima
January 1988,
Sub-cellular biochemistry,
