Hyperbaric Oxygen Therapy for Carbon Monoxide-Induced Delayed Neuropsychiatric Sequelae: Case Report of Two Cases and Relevant Literature Review. 2021

Akira Monji, and Hiroshi Tateishi, and Toru Murakawa, and Jun Matsushima, and Yutaka Kunitake, and Takumi Shiraishi, and Ryohei Kojima, and Takayoshi Inaba, and Takahiro Kato, and Yoshito Mizoguchi
Department of Psychiatry, Faculty of Medicine, Saga University, Saga, Japan.

We herein report two cases with carbon monoxide- (CO-) induced delayed neuropsychiatric sequelae (DNS) successfully treated with hyperbaric oxygen therapy (HBOT) in attempt suicide by charcoal burning. The two patients with CO-induced DNS were successfully treated with a total of more than 100 sessions of HBOT. Frontal assessment battery (FAB) was useful to examine the effectiveness of HBOT objectively. In the future study, a large-randomized trial is required to establish the efficacy of HBOT for the treatment of DNS.

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