-transparent.png){kind=logo}
In a 14 year old boy, a ruptured spleen was removed. Two months after the splenectomy he developed recurrent infections of the respiratory tract. A deficiency of IgA and IgE in his blood serum was found. His impaired resistance to respiratory tract infections responded well to substitution therapy with IgA. Spontaneous clinical recovery occurred during 3 years after the splenectomy, and was parallelled by a slow return of IgA to normal levels, whereas the absence of IgE persisted. The identical twin brother of the patient, who had his spleen intact, had normal levels of serum IgA and did not suffer from frequent respiratory tract inflammations.
Related Publications
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
February 1972,
The Journal of clinical investigation,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
January 1991,
Clinical and experimental rheumatology,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
January 1980,
Annales de pediatrie,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
January 1981,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
November 1970,
The Journal of pediatrics,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
September 1981,
Journal of clinical & laboratory immunology,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
June 1971,
Helvetica paediatrica acta,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
February 2012,
BMJ case reports,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
January 2017,
The journal of allergy and clinical immunology. In practice,
S Skrede, and
F O Winther, and
E Munthe, and
A Nordoy
January 1987,
JAMA,
