Are bio-based and biodegradable microplastics impacting for blue mussel (Mytilus edulis)? 2021

Amina Khalid, and Aurore Zalouk-Vergnoux, and Samira Benali, and Rosica Mincheva, and Jean-Marie Raquez, and Samuel Bertrand, and Laurence Poirier
Laboratoire Mer, Molécules, Santé, Université de Nantes, 2 rue de la Houssinière, BP 92208, 44322 Nantes Cedex 3, France.

The substitution of petrochemical plastics by bio-based and biodegradable plastics are in need of an evaluation for the potential toxic impacts that they can have on marine wildlife. This study aims to assess the toxicological effects of polylactic acid microparticles at two concentrations, 10 and 100 μg/L, during 8 days on the blue mussel, Mytilus edulis. No significant oxidative stress (catalase, glutathione-S-transferase and superoxide dismutase activities), neurotoxicity (acetylcholinesterase), or immunotoxicity (lysosomal membrane stability and acid phosphatase activity) were detectable. The multivariate analysis of metabolomic data allowed us to differentiate the individuals according to the exposure. From the loading plot of OPLS-DA, 48 ions down-regulated in the individuals exposed to microplastics. They were identified based on HRMS data as glycerophospholipids.

UI MeSH Term Description Entries
D010969 Plastics Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Plastic
D002374 Catalase An oxidoreductase that catalyzes the conversion of HYDROGEN PEROXIDE to water and oxygen. It is present in many animal cells. A deficiency of this enzyme results in ACATALASIA. Catalase A,Catalase T,Manganese Catalase,Mn Catalase
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000080545 Microplastics Plastic particles, less than 5 millimeters in diameter, that are generated from the degradation of larger pieces or are manufactured to be microstructures or smaller. Mesoplastics,Plastic Microparticles,Plastic Nanoparticles,Mesoplastic,Microparticle, Plastic,Microparticles, Plastic,Microplastic,Nanoparticle, Plastic,Nanoparticles, Plastic,Plastic Microparticle,Plastic Nanoparticle
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014874 Water Pollutants, Chemical Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water. Chemical Water Pollutants,Landfill Leachate,Leachate, Landfill,Pollutants, Chemical Water
D049878 Mytilus A genus of marine mussels in the family MYTILIDAE, class BIVALVIA. The species MYTILUS EDULIS is the highly edible common mussel.
D049880 Mytilus edulis A species of mussel in the genus MYTILUS, family MYTILIDAE, class BIVALVIA, known as the common mussel. It has a bluish-black shell and is highly edible. Mussels, Blue,Mussels, Common,Mussel, Blue,Mussel, Common,Blue Mussel,Blue Mussels,Common Mussel,Common Mussels,Mytilus eduli,edulis, Mytilus

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