-transparent.png){kind=logo}
A 22-year-old man was found to have low serum urate concentration (1.1-1.7 mg/dl). His urate clearance was markedly increased (26.9-35.5 ml/min) and was not decreased after administration of pyrazinamide, but was even more increased after administration of benzbromarone. No other renal tubular abnormalities were detected. The young man has one sister and two brothers. His sister also has hypouricemia and hyperuricosuria. We suggest that the present case had a genetically determined renal abnormality affecting tubular presecretory reabsorption of urate.
Related Publications
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
January 1980,
Clinical nephrology,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
January 1977,
The Journal of rheumatology,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
January 1982,
Nephron,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
December 1987,
Clinical nephrology,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
May 1980,
The Journal of pediatrics,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
April 1981,
Israel journal of medical sciences,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
January 1977,
Advances in experimental medicine and biology,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
June 1979,
Biomedicine / [publiee pour l'A.A.I.C.I.G.],
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
January 1986,
Advances in experimental medicine and biology,
I Hisatome, and
K Ogino, and
M Saito, and
J Miyamoto, and
J Hasegawa, and
H Kotake, and
H Mashiba, and
S Nakamoto
October 1982,
Archives of internal medicine,
