Skin surface application of ketocaine to provide local anaesthesia for cutting split skin grafts. 1977

B Pontén, and L Ohlsén

Astra 2337 ketocaine-soaked pads applied to the skin surface produced analgesia adequate for split skin graft cutting 85 out of 86 patients. In 86 per cent, the analgesia was completely satisfactory; a few had some discomfort or pain but all could tolerate this. Application for 1 hour is time enough, but the effect lasts for at least 8 hours and probably longer. Apart from occasional redness and oedema of the skin, no adverse effects wer noted and the blood levels of absorbed ketocaine were far below the toxic level. This simple effective technique is of great value, particularly in such cases as burns who require multiple grafting operations and in whom repeated general anaesthetics can have such adverse effect.

UI MeSH Term Description Entries
D008297 Male Males
D011437 Propylamines Derivatives of propylamine (the structural formula NH2CH2CH2CH3).
D002090 Butyrophenones Compounds containing phenyl-1-butanone.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000772 Anesthesia, Local A blocking of nerve conduction to a specific area by an injection of an anesthetic agent. Anesthesia, Infiltration,Local Anesthesia,Neural Therapy of Huneke,Huneke Neural Therapy,Infiltration Anesthesia
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D016038 Skin Transplantation The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin. Dermatoplasty,Grafting, Skin,Transplantation, Skin,Dermatoplasties,Graftings, Skin,Skin Grafting,Skin Graftings,Skin Transplantations,Transplantations, Skin
D062109 Dermatologic Surgical Procedures Operative procedures performed on the SKIN. Cutaneous Surgery,Cutaneous Surgical Procedures,Dermatologic Surgery,Skin Surgery,Cutaneous Surgeries,Cutaneous Surgical Procedure,Dermatologic Surgeries,Dermatologic Surgical Procedure,Procedure, Cutaneous Surgical,Procedure, Dermatologic Surgical,Procedures, Cutaneous Surgical,Procedures, Dermatologic Surgical,Skin Surgeries,Surgeries, Cutaneous,Surgeries, Dermatologic,Surgeries, Skin,Surgery, Cutaneous,Surgery, Dermatologic,Surgery, Skin,Surgical Procedure, Cutaneous,Surgical Procedure, Dermatologic,Surgical Procedures, Cutaneous,Surgical Procedures, Dermatologic

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