Biomaterial Database

The effect of oxygen on in vitro studies on methemoglobin production in man and dog blood using 4-dimethylaminophenol. 1988

A C Woodman, and J E Bright, and T C Marrs

Medical Division Chemical Defence Establishment, Salisbury, Wiltshire, UK.

Methemoglobin production induced by the addition of 4-dimethylaminophenol to human or beagle blood in vitro is inhibited at high oxyhemoglobin levels. The effect is similar in the two species and probably results from conformational change in hemoglobin consequent on oxygen binding.

UI	MeSH Term	Description	Entries
D008706	Methemoglobin		Ferrihemoglobin
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000627	Aminophenols	Phenols substituted in any position by an amino group.	Hydroxyanilines
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D066298	In Vitro Techniques	Methods to study reactions or processes taking place in an artificial environment outside the living organism.	In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In