An EM and Golgi study on the connection between the nucleus tegmenti pedunculopontinus and the pars compacta of the substantia nigra in the rat. 1988

E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
Department of Human Physiology, School of Medicine, University of L'Aquila, Italy.

The present study provides evidence of a synaptic contact between terminals of pedunculopontine neurons and cells of substantia nigra pars compacta (SNPC) in the rat. Three types of projective neurons observed in Golgi stained preparations of the pedunculopontine region might be the source of this afferent pathway to the substantia nigra. These PPN projective neurons were small, medium and large sized cells. After placing a small electrolytic lesion into the pedunculopontine area two types of degenerated terminals were found in the SNPC, a small and a larger one. These degenerated terminals contained round synaptic vesicles, thus suggesting that the pedunculopontine input to the SNPC is monosynaptic and excitatory in nature.

UI MeSH Term Description Entries
D008297 Male Males
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D009410 Nerve Degeneration Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways. Neuron Degeneration,Degeneration, Nerve,Degeneration, Neuron,Degenerations, Nerve,Degenerations, Neuron,Nerve Degenerations,Neuron Degenerations
D009474 Neurons The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM. Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D011919 Rats, Inbred Strains Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations or by parent x offspring matings carried out with certain restrictions. This also includes animals with a long history of closed colony breeding. August Rats,Inbred Rat Strains,Inbred Strain of Rat,Inbred Strain of Rats,Inbred Strains of Rats,Rat, Inbred Strain,August Rat,Inbred Rat Strain,Inbred Strain Rat,Inbred Strain Rats,Inbred Strains Rat,Inbred Strains Rats,Rat Inbred Strain,Rat Inbred Strains,Rat Strain, Inbred,Rat Strains, Inbred,Rat, August,Rat, Inbred Strains,Rats Inbred Strain,Rats Inbred Strains,Rats, August,Rats, Inbred Strain,Strain Rat, Inbred,Strain Rats, Inbred,Strain, Inbred Rat,Strains, Inbred Rat
D001931 Brain Mapping Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures. Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D003712 Dendrites Extensions of the nerve cell body. They are short and branched and receive stimuli from other NEURONS. Dendrite
D000344 Afferent Pathways Nerve structures through which impulses are conducted from a peripheral part toward a nerve center. Afferent Pathway,Pathway, Afferent,Pathways, Afferent
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D013378 Substantia Nigra The black substance in the ventral midbrain or the nucleus of cells containing the black substance. These cells produce DOPAMINE, an important neurotransmitter in regulation of the sensorimotor system and mood. The dark colored MELANIN is a by-product of dopamine synthesis. Nigra, Substantia,Nigras, Substantia,Substantia Nigras

Related Publications

E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
June 1983, The Journal of comparative neurology,
E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
June 1986, Neuroscience letters,
E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
November 2006, The Journal of neuroscience : the official journal of the Society for Neuroscience,
E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
January 2005, The Journal of neuroscience : the official journal of the Society for Neuroscience,
E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
February 1981, Neuroscience letters,
E Scarnati, and F Hajdu, and C Pacitti, and T Tömböl
January 1979, The Japanese journal of physiology,
Copied contents to your clipboard!