Classifying the Risk of Cognitive Impairment Using Sequential Gait Characteristics and Long Short-Term Memory Networks. 2021

Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun

Cognitive impairment in the elderly causes a significant decline in the quality of life and a substantial economic burden on society. Yet, diagnosing cognitive impairment is apt to be missed or delayed due to its assessment being laborious. This study aimed to propose a new approach of classifying the risk of cognitive impairment in the elderly using sequential gait characteristics and machine learning techniques. A total of 108 community-dwelling elderly individuals participated in this study. The participants were categorized into three groups based on their scores of the mini-mental state examination. Each participant completed both the usual- and fast-paced walking on the straight path with two gyroscopes on each foot. By analyzing the foot sagittal angular velocity signals, the temporal gait parameters were extracted from each gait cycle. Five classical machine learning models and a long short-term memory network were respectively employed to produce the classifiers that used the time-consecutive temporal gait parameters as predictors of cognitive impairment. Five-fold cross-validation was applied to 70% of the data in each group, and the remaining 30% were used as test data. An F1-score of 0.974 was achieved in classifying the three groups by the long short-term memory network-based classifier that used the double-limb support, stance, step, and stride times at usual-paced walking and the double- and single-limb support, stance, and stride times at fast-paced walking as inputs. The proposed approach would pave the way for earlier diagnosis of cognitive impairment in non-clinical settings without professional help, which can facilitate more timely intervention.

UI MeSH Term Description Entries
D008570 Memory, Short-Term Remembrance of information for a few seconds to hours. Immediate Recall,Memory, Immediate,Working Memory,Memory, Shortterm,Immediate Memories,Immediate Memory,Immediate Recalls,Memories, Immediate,Memories, Short-Term,Memories, Shortterm,Memory, Short Term,Recall, Immediate,Recalls, Immediate,Short-Term Memories,Short-Term Memory,Shortterm Memories,Shortterm Memory,Working Memories
D011788 Quality of Life A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease. HRQOL,Health-Related Quality Of Life,Life Quality,Health Related Quality Of Life
D005684 Gait Manner or style of walking. Gaits
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D016138 Walking An activity in which the body advances at a slow to moderate pace by moving the feet in a coordinated fashion. This includes recreational walking, walking for fitness, and competitive race-walking. Ambulation
D060825 Cognitive Dysfunction Diminished or impaired mental and/or intellectual function. Cognitive Disorder,Mild Cognitive Impairment,Cognitive Decline,Cognitive Impairments,Mental Deterioration,Cognitive Declines,Cognitive Disorders,Cognitive Dysfunctions,Cognitive Impairment,Cognitive Impairment, Mild,Cognitive Impairments, Mild,Decline, Cognitive,Declines, Cognitive,Deterioration, Mental,Deteriorations, Mental,Disorder, Cognitive,Disorders, Cognitive,Dysfunction, Cognitive,Dysfunctions, Cognitive,Impairment, Cognitive,Impairment, Mild Cognitive,Impairments, Cognitive,Impairments, Mild Cognitive,Mental Deteriorations,Mild Cognitive Impairments

Related Publications

Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
January 2019, BMC bioinformatics,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
January 2021, PloS one,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
January 2024, IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
June 2025, Physical and engineering sciences in medicine,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
April 2019, Sensors (Basel, Switzerland),
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
December 2021, Current genomics,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
December 2019, Protein engineering, design & selection : PEDS,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
July 2025, Physical and engineering sciences in medicine,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
January 1967, The Journal of psychology,
Dawoon Jung, and Jinwook Kim, and Miji Kim, and Chang Won Won, and Kyung-Ryoul Mun
December 2022, IEEE journal of biomedical and health informatics,
Copied contents to your clipboard!