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Infective Endocarditis from Furuncle with Meningitis Complication Caused by Methicillin-resistant Staphylococcus aureus. 2021
Shusuke Yagi, and
Tomoko Takahashi, and
Keiji Murakami, and
Momoyo Azuma, and
Mikio Sugano, and
Ryosuke Miyamoto, and
Mariko Niki, and
Hirotsugu Yamada, and
Yutaka Kawabata, and
Akihiro Tani, and
Daiju Fukuda, and
Muneyuki Kadota, and
Takayuki Ise, and
Kenya Kusunose, and
Takeshi Tobiume, and
Tomomi Matsuura, and
Koji Yamaguchi, and
Takeshi Soeki, and
Tetsuzo Wakatsuki, and
Hiroki Hata, and
Masataka Sata
Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences, Japan.
Infective endocarditis (IE) may be acquired in the community as community-acquired (CA) IE or in the healthcare setting. In Japan, cases of CA-methicillin-resistant Staphylococcus aureus (MRSA) infection as skin infection have been increasing. CA-MRSA strains, including the USA300 clone, have higher pathogenicity and are more destructive to tissue than healthcare-associated MRSA strains because of the toxins they produce, including arginine-catabolic mobile element (ACME) and Panton-Valentine leukocidin (PVL). However, only a few IE cases induced by USA300 have been reported. We herein report a 64-year-old man who developed CA-IE from a furuncle caused by USA300 MRSA producing PVL and ACME, which resulted in complications of meningitis.
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