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Bioorthogonal control of the phosphorescence and singlet oxygen photosensitisation properties of iridium(III) tetrazine complexes. 2021

Peter Kam-Keung Leung, and Lawrence Cho-Cheung Lee, and Herman Ho-Yin Yeung, and Kai-Wa Io, and Kenneth Kam-Wing Lo
Department of Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, P. R. China. bhkenlo@cityu.edu.hk.

In this work, we demonstrate bioorthogonal control of the phosphorescence and singlet oxygen photosensitisation properties of new iridium(iii) tetrazine complexes by different reaction partners; the system was exploited for organelle-specific staining and modulated photocytotoxic activity applications.

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