Biomaterial Database

Arterial Function after a 246 km Ultra-marathon Running Race. 2021

Nikolaos Koutlianos, and Panagiota Sotiriou, and Georgios Christou, and Efstathios Pagourelias, and Maria Anifanti, and Konstantinos Christou, and Maria Tsironi, and Panagiotis Andriopoulos, and Evangelia Kouidi, and Asterios Deligiannis

Department of Physical Education & Sports Science, Aristotle University of Thessaloniki, Sports Medicine Laboratory, Thermi, Greece.

There is little research about the effects of ultra-endurance exercise on arterial morphological and functional properties. The aim was to assess the acute changes of the carotid-femoral pulse wave velocity and carotid doppler-derived parameters following an ultra-marathon race as well as the intima-media thickness of the carotid artery in ultra-marathon runners. Twenty athletes were examined at baseline and within 10 mins after a 246 km running race. Measurements included carotid-femoral pulse wave velocity, peak-systolic and end-diastolic velocities of carotid artery blood flow, pulsatility and resistivity indices and blood biochemical parameters. The intima-media thickness of the right and left carotid artery was measured before the race. Arterial stiffness and carotid artery intima media thickness at rest remained within known normal limits. The ultra-marathon race significantly increased carotid-femoral pulse wave velocity by 22.6% and pulsatility index by 10.2%. There was a decrease in body weight by 3.35% and an increase of all biochemical markers of muscle damage after the race. Additionally, C-reactive protein was correlated with both pulsatility and resistivity indices post-race. This study shows that immediately after a 246 km ultra-marathon running race, acute increase of arterial stiffness and vascular resistance were evident. The carotid artery thickness of ultra-marathon runners was within normal range.

UI	MeSH Term	Description	Entries
D002339	Carotid Arteries	Either of the two principal arteries on both sides of the neck that supply blood to the head and neck; each divides into two branches, the internal carotid artery and the external carotid artery.	Arteries, Carotid,Artery, Carotid,Carotid Artery
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000081642	Marathon Running	A sporting event in which participants run a distance of approximately 26.2 miles in a race.	Marathons,Ultramarathon Running,Marathon,Running, Marathon,Running, Ultramarathon
D014655	Vascular Resistance	The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.	Peripheral Resistance,Total Peripheral Resistance,Pulmonary Vascular Resistance,Systemic Vascular Resistance,Peripheral Resistance, Total,Resistance, Peripheral,Resistance, Pulmonary Vascular,Resistance, Systemic Vascular,Resistance, Total Peripheral,Resistance, Vascular,Vascular Resistance, Pulmonary,Vascular Resistance, Systemic
D056352	Athletes	Individuals who have developed skills, physical stamina and strength or participants in SPORTS or other physical activities.	College Athletes,Elite Athletes,Professional Athletes,Athlete,Athlete, College,Athlete, Elite,Athlete, Professional,Athletes, College,Athletes, Elite,Athletes, Professional,College Athlete,Elite Athlete,Professional Athlete
D059168	Carotid Intima-Media Thickness	A measurement of the thickness of the carotid artery walls. It is measured by B-mode ULTRASONOGRAPHY and is used as a surrogate marker for ATHEROSCLEROSIS.	Carotid Intima Media Thickness,Intima-Media Thickness, Carotid
D059289	Vascular Stiffness	Loss of vascular ELASTICITY due to factors such as AGING; and ARTERIOSCLEROSIS. Increased arterial stiffness is one of the RISK FACTORS for many CARDIOVASCULAR DISEASES.	Arterial Stiffness,Aortic Stiffness,Aortic Stiffnesses,Arterial Stiffnesses,Stiffness, Aortic,Stiffness, Arterial,Stiffness, Vascular,Vascular Stiffnesses
D063177	Pulse Wave Analysis	Evaluation of the contour of the PULSE waves which vary in different parts of the circulation and depend on physiological as well as pathophysiological conditions of the individual.	Pulse Transit Time,Pulse Wave Transit Time,Pulse Wave Velocity,Analyses, Pulse Wave,Analysis, Pulse Wave,Pulse Transit Times,Pulse Wave Analyses,Pulse Wave Velocities,Time, Pulse Transit,Times, Pulse Transit,Transit Time, Pulse,Transit Times, Pulse,Velocities, Pulse Wave,Velocity, Pulse Wave,Wave Analyses, Pulse,Wave Analysis, Pulse,Wave Velocities, Pulse,Wave Velocity, Pulse