-transparent.png){kind=logo}
Antithrombin III (AT III) is a major modulator of the clotting cascade and is decreased in disseminated intravascular coagulation (DIC). AT III was given as a pretreatment to dogs with endotoxin-induced DIC. Significant improvement in clotting parameters (prothrombin time, fibrinogen, fibrin degradation products) was noted. There was no effect on platelets. Mean arterial blood pressure was improved, while there were no other significant changes in other measured hemodynamic, acid-base, or biochemical variables. It was concluded that AT III was effective in ameliorating endotoxin-induced changes in the clotting profile. AT III may prove to be a beneficial therapy in acquired DIC.
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
April 1980,
American journal of clinical pathology,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
April 1978,
Lancet (London, England),
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
June 1978,
Lancet (London, England),
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
January 1977,
Folia haematologica (Leipzig, Germany : 1928),
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
January 1983,
Nephron,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
February 1997,
Ugeskrift for laeger,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
May 1989,
Circulatory shock,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
October 1974,
Canadian journal of comparative medicine : Revue canadienne de medecine comparee,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
February 1992,
Sangre,
J G Hauptman, and
H I Hassouna, and
T G Bell, and
J A Penner, and
T E Emerson
June 1982,
[Rinsho ketsueki] The Japanese journal of clinical hematology,
