-transparent.png){kind=logo}
•AAV is characterized by necrotizing small vessel vasculitis with positive serum ANCA.•MPO/PR3-ANCA and neutrophils play central roles in AAV pathogenicity.•Dysregulated complement system primes neutrophils.•MPO-ANCA directly activates neutrophils to induce NETosis followed by releasing NETs.•B cells, T cells, and dendritic cells also contribute to the pathogenicity of AAV.
| UI | MeSH Term | Description | Entries |
|---|
Related Publications
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
June 2013,
Revista medica de Chile,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
May 2011,
Clinical and experimental immunology,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
October 2023,
Cureus,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
January 2016,
Internal medicine (Tokyo, Japan),
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
March 2023,
Rheumatology and immunology research,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
May 2011,
Clinical and experimental immunology,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
December 2023,
The Annals of pharmacotherapy,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
August 1999,
Clinical and experimental immunology,
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
March 2006,
Rheumatology (Oxford, England),
Daisuke Tsukui, and
Yoshitaka Kimura, and
Hajime Kono
June 2012,
Arthritis research & therapy,
