-transparent.png){kind=logo}
We compared the cognitive effects of carbamazepine and phenytoin with neuropsychological tests exploring intelligence, vigilance, attention, memory, and visuomotor performances in 25 epileptics (13 receiving carbamazepine and 12 receiving phenytoin) and 26 matched normal controls. Patients were seizure free for at least two years and taking prolonged monotherapy. We also evaluated the effects of drug withdrawal by retesting patients three months after reduction at half drug dose and three months and one year after complete withdrawal. Our findings suggest that phenytoin affects the cognitive functions more than carbamazepine does, although the negative effects of both drugs are reversible by complete therapy withdrawal.
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
May 2010,
Clinical neurology and neurosurgery,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
February 1994,
Acta neurologica Scandinavica,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
September 1993,
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
January 1986,
Therapeutic drug monitoring,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
January 1983,
Acta neurologica Scandinavica. Supplementum,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
August 1992,
Acta neurologica Scandinavica,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
June 1993,
The Annals of pharmacotherapy,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
March 1986,
Journal of neurology, neurosurgery, and psychiatry,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
January 1988,
Epilepsia,
R Gallassi, and
A Morreale, and
S Lorusso, and
G Procaccianti, and
E Lugaresi, and
A Baruzzi
February 2022,
Epilepsy & behavior : E&B,
