BIOMAT Database Logo BIOMAT Database Logo

The role of radiotherapy in adult soft tissues sarcoma of the extremities. 2021

Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Radiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. silvia.cammelli2@unibo.it.

Local management of adult soft tissue sarcoma of the extremities has evolved over the past decades. Until the 1970s, radical surgery (amputations) was the standard therapeutic procedure resulting in significant physical and psychological morbidity for the patients. In the present era, limb sparing surgery combined with radiotherapy represents the current standard of care for high grade and > 5 cm STSs. This approach guarantees high local control rate and function preservation. The aim of this paper is to summarize the current evidence for RT in STSs of the extremities. Outcomes, technical details (techniques, timing, dose, volumes of treatment) and the emerging role of RT in the management of oligometastatic disease will be analysed. Finally, results of the recent clinical trials testing new scenarios in RT of STSs will be described.

UI MeSH Term Description Entries
D005121 Extremities The farthest or outermost projections of the body, such as the HAND and FOOT. Limbs,Extremity,Limb
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000671 Amputation, Surgical The surgical removal of part of, or all of, a limb or other appendage or outgrowth of the body. Amputation,Amputation, Multiple, Surgical,Multiple Amputation, Surgical,Surgical Amputation Procedures,Amputation Procedure, Surgical,Amputation Procedures, Surgical,Amputation, Surgical Multiple,Amputations,Amputations, Surgical,Amputations, Surgical Multiple,Multiple Amputations, Surgical,Procedure, Surgical Amputation,Procedures, Surgical Amputation,Surgical Amputation,Surgical Amputation Procedure,Surgical Amputations,Surgical Multiple Amputation,Surgical Multiple Amputations
D012509 Sarcoma A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. Sarcoma, Epithelioid,Sarcoma, Soft Tissue,Sarcoma, Spindle Cell,Epithelioid Sarcoma,Epithelioid Sarcomas,Sarcomas,Sarcomas, Epithelioid,Sarcomas, Soft Tissue,Sarcomas, Spindle Cell,Soft Tissue Sarcoma,Soft Tissue Sarcomas,Spindle Cell Sarcoma,Spindle Cell Sarcomas
D012983 Soft Tissue Neoplasms Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc. Neoplasm, Soft Tissue,Neoplasms, Soft Tissue,Soft Tissue Neoplasm
D018714 Radiotherapy, Adjuvant Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment. Adjuvant Radiotherapy,Adjuvant Radiotherapies,Radiotherapies, Adjuvant

Related Publications

Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Radiotherapy in soft tissue sarcoma of the extremities.
February 1997, Acta orthopaedica Scandinavica. Supplementum,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Radiotherapy in soft-tissue sarcoma of the extremities.
September 2018, Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
[Intraoperative radiotherapy in advanced soft tissue sarcoma of the extremities].
January 1996, Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
[Effectiveness of radiotherapy in sarcoma of the soft tissues].
January 1958, Vestnik rentgenologii i radiologii,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
[Radiotherapy of adult soft tissue sarcoma].
September 2016, Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
[Surgical treatment of sarcoma of the soft tissues of the extremities].
July 1978, Vestnik khirurgii imeni I. I. Grekova,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
[Role of radiotherapy in soft tissue sarcoma].
January 1997, Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Adjuvant radiotherapy in the management of soft tissue sarcoma involving the distal extremities.
February 2006, American journal of clinical oncology,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Patterns of Practice Survey: Radiotherapy for Soft Tissue Sarcoma of the Extremities.
November 2019, Cureus,
Silvia Cammelli, and Annalisa Cortesi, and Milly Buwenge, and Alice Zamagni, and Martina Ferioli, and Giulia Ghigi, and Antonino Romeo, and Alessio G Morganti
Management of adult soft-tissue sarcoma of the extremities and trunk.
February 2010, Expert review of anticancer therapy,
Copied contents to your clipboard!