Biomaterial Database

Potential Mechanisms of COVID-19-Related Psychological Problems and Mental Disorders. 2021

Alfred Shaw

Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Beijing, China. springwindxiao@163.com.

As the coronavirus disease 2019 (COVID-19) pandemic has spread, so has the psychological impact of the disease been felt worldwide. Despite this, the mechanisms of COVID-19-related psychological problems and mental disorders remain unclear. As such, effective therapeutic schemes or intervention strategies cannot be developed. It is, therefore, necessary to establish a theoretical basis of psychological problems and mental disorders related to public health emergencies such as COVID-19. Herein, the potential mechanisms of occurrence and development of COVID-19-related psychological problems and mental disorders have been discussed from two angles: the pandemic as a public health emergency itself and the extensive quarantine situation during the pandemic.

UI	MeSH Term	Description	Entries
D011790	Quarantine	Limited freedom of movement of individuals to reduce the risk of spread of communicable disease by those who have been exposed to infectious or communicable disease in order to prevent its spread; a period of detention of vessels, vehicles, or travelers coming from infected or suspected places; and detention or isolation on account of suspected contagion. It includes government regulations on travel restrictions, border security measures to mitigate spread of a contagion and the detention of animals at frontiers or ports of entrance for the prevention of infectious disease. (From Black's Veterinary Dictionary, 17th ed)	Border Closing, Health-Related,Border Travel Restrictions, Health-Related,Cordon Sanitaire,Health-Related Border Travel Restrictions,Health-Related Travel Restriction,Health-Related Travel Restrictions,Lockdown, Health,Self-Quarantine,Stay at Home Orders,Travel Restriction, Health,Travel Restrictions, Health-Related,Border Closing, Health Related,Border Closings, Health-Related,Border Travel Restrictions, Health Related,Health Lockdown,Health Lockdowns,Health Related Border Travel Restrictions,Health Related Travel Restriction,Health Related Travel Restrictions,Health Travel Restriction,Health Travel Restrictions,Health-Related Border Closing,Health-Related Border Closings,Quarantines,Self Quarantine,Travel Restriction, Health-Related,Travel Restrictions, Health,Travel Restrictions, Health Related
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000086382	COVID-19	A viral disorder generally characterized by high FEVER; COUGH; DYSPNEA; CHILLS; PERSISTENT TREMOR; MUSCLE PAIN; HEADACHE; SORE THROAT; a new loss of taste and/or smell (see AGEUSIA and ANOSMIA) and other symptoms of a VIRAL PNEUMONIA. In severe cases, a myriad of coagulopathy associated symptoms often correlating with COVID-19 severity is seen (e.g., BLOOD COAGULATION; THROMBOSIS; ACUTE RESPIRATORY DISTRESS SYNDROME; SEIZURES; HEART ATTACK; STROKE; multiple CEREBRAL INFARCTIONS; KIDNEY FAILURE; catastrophic ANTIPHOSPHOLIPID ANTIBODY SYNDROME and/or DISSEMINATED INTRAVASCULAR COAGULATION). In younger patients, rare inflammatory syndromes are sometimes associated with COVID-19 (e.g., atypical KAWASAKI SYNDROME; TOXIC SHOCK SYNDROME; pediatric multisystem inflammatory disease; and CYTOKINE STORM SYNDROME). A coronavirus, SARS-CoV-2, in the genus BETACORONAVIRUS is the causative agent.	2019 Novel Coronavirus Disease,2019 Novel Coronavirus Infection,2019-nCoV Disease,2019-nCoV Infection,COVID-19 Pandemic,COVID-19 Pandemics,COVID-19 Virus Disease,COVID-19 Virus Infection,Coronavirus Disease 2019,Coronavirus Disease-19,SARS Coronavirus 2 Infection,SARS-CoV-2 Infection,Severe Acute Respiratory Syndrome Coronavirus 2 Infection,COVID19,2019 nCoV Disease,2019 nCoV Infection,2019-nCoV Diseases,2019-nCoV Infections,COVID 19,COVID 19 Pandemic,COVID 19 Virus Disease,COVID 19 Virus Infection,COVID-19 Virus Diseases,COVID-19 Virus Infections,Coronavirus Disease 19,Disease 2019, Coronavirus,Disease, 2019-nCoV,Disease, COVID-19 Virus,Infection, 2019-nCoV,Infection, COVID-19 Virus,Infection, SARS-CoV-2,Pandemic, COVID-19,SARS CoV 2 Infection,SARS-CoV-2 Infections,Virus Disease, COVID-19,Virus Infection, COVID-19
D000086402	SARS-CoV-2	A species of BETACORONAVIRUS causing atypical respiratory disease (COVID-19) in humans. The organism was first identified in 2019 in Wuhan, China. The natural host is the Chinese intermediate horseshoe bat, RHINOLOPHUS affinis.	2019 Novel Coronavirus,COVID-19 Virus,COVID19 Virus,Coronavirus Disease 2019 Virus,SARS Coronavirus 2,SARS-CoV-2 Virus,Severe Acute Respiratory Syndrome Coronavirus 2,Wuhan Coronavirus,Wuhan Seafood Market Pneumonia Virus,2019-nCoV,2019 Novel Coronaviruses,COVID 19 Virus,COVID-19 Viruses,COVID19 Viruses,Coronavirus 2, SARS,Coronavirus, 2019 Novel,Coronavirus, Wuhan,Novel Coronavirus, 2019,SARS CoV 2 Virus,SARS-CoV-2 Viruses,Virus, COVID-19,Virus, COVID19,Virus, SARS-CoV-2,Viruses, COVID19
D001523	Mental Disorders	Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.	Mental Illness,Psychiatric Diseases,Psychiatric Disorders,Psychiatric Illness,Behavior Disorders,Diagnosis, Psychiatric,Mental Disorders, Severe,Psychiatric Diagnosis,Illness, Mental,Mental Disorder,Mental Disorder, Severe,Mental Illnesses,Psychiatric Disease,Psychiatric Disorder,Psychiatric Illnesses,Severe Mental Disorder,Severe Mental Disorders
D058873	Pandemics	Epidemics of infectious disease that have spread to many countries, often more than one continent, and usually affecting a large number of people.	Pandemic