-transparent.png){kind=logo}
The level of the ST-segment fluctuates transiently during treadmill exercise in some patients with angina pectoris. In the present study, the incidence and clinical significance of ST-segment fluctuation were studied before and after propranolol in 52 patients with angina pectoris. A transient greater than 0.5-mm (0.05 mV) upward shift of the ST-segment during a graded treadmill test was considered a significant fluctuation in leads without signs of previous myocardial infarction. The fluctuation was observed in three of 30 patients with rest or rest and effort angina pectoris before propranolol and in 14 of them after propranolol, while only one of 22 patients with effort angina alone showed fluctuation after the drug. Coronary arteriography revealed that in 15 patients showing ST-segment fluctuation with propranolol, seven patients had no significant coronary stenosis, six had one-vessel disease and two had two-vessel disease. In 24 patients with documented coronary artery spasm, ST-segment fluctuation was induced in two (8%) before propranolol and in 13 (54%) after propranolol. Our results suggest that ST-segment fluctuation during graded treadmill exercise may be related to transient coronary vasospasms exacerbated by propranolol.
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
February 2007,
Journal of internal medicine,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
September 2010,
International journal of cardiology,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
March 1985,
Japanese heart journal,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
April 1975,
British heart journal,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
January 1994,
Cardiology,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
January 1983,
Acta medica Scandinavica,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
November 1976,
British heart journal,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
February 1984,
American heart journal,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
January 1997,
The American journal of cardiology,
H Asanoi, and
M Kuboki, and
M Yamamoto, and
T Aizawa, and
J Fujii, and
N Takahashi, and
S Koyama, and
K Kato
January 1997,
Progress in cardiovascular nursing,
