Biomaterial Database

Anterior temporal lobectomy for the control of partial complex seizures: information for counseling patients. 1988

R J Ivnik, and F W Sharbrough, and E R Laws

Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905.

We examined the effect of anterior temporal lobectomy on cognitive function in the treatment of intractable partial complex seizures in a sample of 142 patients. Our current results replicate previous work in this area and clearly establish the presence of differential effects on cognitive function as a consequence of the side of the operation. Learning and memory are most susceptible to impairment postoperatively, although general intellectual abilities are also affected in a small number of patients. The data are further analyzed in a manner that permits determination of the probability of cognitive alterations postoperatively for individual patients. Information is provided to assist health-care professionals in evaluating the risk-to-benefit ratio relative to cognitive abilities as they consider this treatment alternative for their patients who suffer from intractable partial complex seizures.

UI	MeSH Term	Description	Entries
D007361	Intelligence Tests	Standardized tests that measure the present general ability or aptitude for intellectual performance.	Mental Tests,Raven Test,Raven's Progressive Matrices,Intelligence Test,Mental Test,Raven Progressive Matrices,Ravens Progressive Matrices,Test, Intelligence,Test, Mental,Test, Raven
D007858	Learning	Relatively permanent change in behavior that is the result of past experience or practice. The concept includes the acquisition of knowledge.	Phenomenography
D008297	Male		Males
D008568	Memory	Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
D011597	Psychomotor Performance	The coordination of a sensory or ideational (cognitive) process and a motor activity.	Perceptual Motor Performance,Sensory Motor Performance,Visual Motor Coordination,Coordination, Visual Motor,Coordinations, Visual Motor,Motor Coordination, Visual,Motor Coordinations, Visual,Motor Performance, Perceptual,Motor Performance, Sensory,Motor Performances, Perceptual,Motor Performances, Sensory,Perceptual Motor Performances,Performance, Perceptual Motor,Performance, Psychomotor,Performance, Sensory Motor,Performances, Perceptual Motor,Performances, Psychomotor,Performances, Sensory Motor,Psychomotor Performances,Sensory Motor Performances,Visual Motor Coordinations
D011612	Psychosurgery	Treatment of chronic, severe and intractable psychiatric disorders by surgical removal or interruption of certain areas or pathways in the brain, especially in the prefrontal lobes.	Gyrectomy,Leucotomy,Leukotomy,Lobotomy,Topectomy,Gyrectomies,Leucotomies,Leukotomies,Lobotomies,Psychosurgeries,Topectomies
D003071	Cognition	Intellectual or mental process whereby an organism obtains knowledge.	Cognitive Function,Cognitions,Cognitive Functions,Function, Cognitive,Functions, Cognitive
D003376	Counseling	The giving of advice and assistance to individuals with educational or personal problems.
D004833	Epilepsy, Temporal Lobe	A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).	Epilepsy, Benign Psychomotor, Childhood,Benign Psychomotor Epilepsy, Childhood,Childhood Benign Psychomotor Epilepsy,Epilepsy, Lateral Temporal,Epilepsy, Uncinate,Epilepsies, Lateral Temporal,Epilepsies, Temporal Lobe,Epilepsies, Uncinate,Lateral Temporal Epilepsies,Lateral Temporal Epilepsy,Temporal Lobe Epilepsies,Temporal Lobe Epilepsy,Uncinate Epilepsies,Uncinate Epilepsy
D005260	Female		Females