Biomaterial Database

Use of pseudorandom noise in studies of auditory evoked potentials. 1988

A R Møller, and R M Angelo

Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.

The extent to which sensorineural systems such as the auditory system are nonlinear depends on the type of stimulus that is used, and the part of the system from which recordings are made. An estimate of the first-order Wiener kernel of the evoked response from the inferior colliculus to amplitude-modulated tones and noise was obtained by cross-correlating the response with the same pseudorandom noise as was used to amplitude modulate the sounds that were used as stimuli, in order to characterize the linear portion of the system. The shape of these cross-correlograms resembled the potentials evoked to short bursts of the unmodulated tones and noise. The degree of nonlinearity in the response to amplitude-modulated tones and noise was determined, and information about the type of nonlinearity was obtained using the inverse-repeat feature of the pseudorandom noise. Recordings both from the surface and from deep in the nucleus of the inferior colliculus revealed nonlinearities that were predominantly of an even order, but the magnitude of the nonlinearities depended on what stimulus was used, the stimulus intensity, and from which neural structure the recording was made.

UI	MeSH Term	Description	Entries
D007245	Inferior Colliculi	The posterior pair of the quadrigeminal bodies which contain centers for auditory function.	Colliculus, Inferior,Brachial Nucleus of the Inferior Colliculus,Caudal Colliculus,Colliculus Inferior,Inferior Colliculus,Posterior Colliculus,Colliculi, Inferior,Colliculus Inferiors,Colliculus, Caudal,Colliculus, Posterior,Inferior, Colliculus,Inferiors, Colliculus
D008959	Models, Neurological	Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.	Neurologic Models,Model, Neurological,Neurologic Model,Neurological Model,Neurological Models,Model, Neurologic,Models, Neurologic
D009622	Noise	Any sound which is unwanted or interferes with HEARING other sounds.	Noise Pollution,Noises,Pollution, Noise
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D011930	Reaction Time	The time from the onset of a stimulus until a response is observed.	Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D004423	Ear	The hearing and equilibrium system of the body. It consists of three parts: the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR. Sound waves are transmitted through this organ where vibration is transduced to nerve signals that pass through the ACOUSTIC NERVE to the CENTRAL NERVOUS SYSTEM. The inner ear also contains the vestibular organ that maintains equilibrium by transducing signals to the VESTIBULAR NERVE.	Vestibulocochlear System,Vestibulocochlear Apparatus,Apparatus, Vestibulocochlear,Ears,System, Vestibulocochlear
D005072	Evoked Potentials, Auditory	The electric response evoked in the CEREBRAL CORTEX by ACOUSTIC STIMULATION or stimulation of the AUDITORY PATHWAYS.	Auditory Evoked Potentials,Auditory Evoked Response,Auditory Evoked Potential,Auditory Evoked Responses,Evoked Potential, Auditory,Evoked Response, Auditory,Evoked Responses, Auditory,Potentials, Auditory Evoked
D000161	Acoustic Stimulation	Use of sound to elicit a response in the nervous system.	Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia