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In this randomized, prospective study of 91 patients undergoing operations on the colon, we found that neomycin, neomycin-phthalylsulfathiazole and neomycin-erythromycin base all provided adequate intestinal antisepsis. Wound infection rates for all groups were also similar and close to the national average for operations on the colon. A detailed analysis of the wound infections in our series revealed that 60 per cent of these infections were from organisms different from those found on the colonic mucosa. This evidence indicates the possible advantage of parenteral antibiotic therapy to achieve adequate tissue levels of antibiotics not presently possible with orally administered agents.
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
June 1987,
The Pediatric infectious disease journal,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
September 1959,
The American journal of physiology,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
September 1950,
Nature,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
February 1981,
The Journal of pediatrics,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
November 1978,
Pediatrics,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
September 1977,
Annals of surgery,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
October 1975,
American journal of hospital pharmacy,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
August 1955,
Journal of the American Geriatrics Society,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
May 1971,
The Journal of pediatrics,
T Vargish, and
L C Crawford, and
R A Stallings, and
B L Wasilauskas, and
R T Myers
October 1965,
California medicine,
