Protein kinase C--structural studies. 1988

P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
Ludwig Institute for Cancer Research, London, England.

UI MeSH Term Description Entries
D011493 Protein Kinase C An serine-threonine protein kinase that requires the presence of physiological concentrations of CALCIUM and membrane PHOSPHOLIPIDS. The additional presence of DIACYLGLYCEROLS markedly increases its sensitivity to both calcium and phospholipids. The sensitivity of the enzyme can also be increased by PHORBOL ESTERS and it is believed that protein kinase C is the receptor protein of tumor-promoting phorbol esters. Calcium Phospholipid-Dependent Protein Kinase,Calcium-Activated Phospholipid-Dependent Kinase,PKC Serine-Threonine Kinase,Phospholipid-Sensitive Calcium-Dependent Protein Kinase,Protein Kinase M,Calcium Activated Phospholipid Dependent Kinase,Calcium Phospholipid Dependent Protein Kinase,PKC Serine Threonine Kinase,Phospholipid Sensitive Calcium Dependent Protein Kinase,Phospholipid-Dependent Kinase, Calcium-Activated,Serine-Threonine Kinase, PKC
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D004247 DNA A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine). DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D004789 Enzyme Activation Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. Activation, Enzyme,Activations, Enzyme,Enzyme Activations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014158 Transcription, Genetic The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION. Genetic Transcription
D046911 Macromolecular Substances Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. Macromolecular Complexes,Macromolecular Compounds,Macromolecular Compounds and Complexes,Complexes, Macromolecular,Compounds, Macromolecular,Substances, Macromolecular

Related Publications

P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
January 1988, Advances in experimental medicine and biology,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
October 1988, The Journal of biological chemistry,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
March 1999, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
January 1991, Journal of molecular structure,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
March 1985, Biochemical and biophysical research communications,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
January 1982, Annals of the New York Academy of Sciences,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
January 2003, Methods in molecular biology (Clifton, N.J.),
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
October 2008, Physiological reviews,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
March 2012, Expert opinion on therapeutic targets,
P J Parker, and R Marais, and M Bajaj, and F Mitchell, and P King, and S Young, and A Ullrich, and S Stabel
February 1996, Seikagaku. The Journal of Japanese Biochemical Society,
Copied contents to your clipboard!