Biomaterial Database

Deep-inspiration breath hold radiotherapy in patients with left-sided breast cancer after partial mastectomy. 2021

M Doležel, and K Odrážka, and J Vaňásek

The purpose of this study was to compare the radiation dose to organs at risk for deep-inspiration breath hold (DIBH) and free-breathing (FB) radiotherapy in patients with lef-sided breast cancer undergoing adjuvant radiotherapy after partial mastectomy. Methods: One hundred patients with left-sided breast cancer underwent DIBH and FB planning computed tomography scans, and the 2 techniques were compared. Dose-volume histograms were analyzed for heart, left anterior descending coronary artery (LAD), and left lung. Results: Radiation dose to heart, LAD, and left lung was significantly lower for DIBH than for free breathing plans. The median mean heart dose for DIBH technique in comparison with FB was 1.21 Gy, and 3.22 Gy respectively; for LAD, 4.67 versus 24.71 Gy; and for left lung 8.32 Gy versus 9.99 Gy. Conclusion: DIBH is an effective technique to reduce cardiac and lung radiation exposure.

UI	MeSH Term	Description	Entries
D008408	Mastectomy	Surgical procedure to remove one or both breasts.	Mammectomy,Mammectomies,Mastectomies
D011879	Radiotherapy Dosage	The total amount of radiation absorbed by tissues as a result of radiotherapy.	Dosage, Radiotherapy,Dosages, Radiotherapy,Radiotherapy Dosages
D011880	Radiotherapy Planning, Computer-Assisted	Computer-assisted mathematical calculations of beam angles, intensities of radiation, and duration of irradiation in radiotherapy.	Computer-Assisted Radiotherapy Planning,Dosimetry Calculations, Computer-Assisted,Planning, Computer-Assisted Radiotherapy,Calculation, Computer-Assisted Dosimetry,Calculations, Computer-Assisted Dosimetry,Computer Assisted Radiotherapy Planning,Computer-Assisted Dosimetry Calculation,Computer-Assisted Dosimetry Calculations,Dosimetry Calculation, Computer-Assisted,Dosimetry Calculations, Computer Assisted,Planning, Computer Assisted Radiotherapy,Radiotherapy Planning, Computer Assisted
D001943	Breast Neoplasms	Tumors or cancer of the human BREAST.	Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000069584	Unilateral Breast Neoplasms	Tumors or cancer found specifically in one human BREAST, but not in both.	Left Sided Breast Cancer,Left Sided Breast Neoplasm,Left Sided Breast Neoplasms,Left-Sided Breast Cancer,Left-Sided Breast Neoplasms,Right Sided Breast Cancer,Right Sided Breast Neoplasm,Right-Sided Breast Cancer,Right-Sided Breast Neoplasms,Unilateral Breast Cancer,Breast Cancer, Left-Sided,Breast Cancer, Right-Sided,Breast Cancer, Unilateral,Breast Cancers, Left-Sided,Breast Cancers, Right-Sided,Breast Cancers, Unilateral,Breast Neoplasm, Left-Sided,Breast Neoplasm, Right-Sided,Breast Neoplasm, Unilateral,Breast Neoplasms, Left-Sided,Breast Neoplasms, Right-Sided,Breast Neoplasms, Unilateral,Left-Sided Breast Cancers,Left-Sided Breast Neoplasm,Right Sided Breast Neoplasms,Right-Sided Breast Cancers,Right-Sided Breast Neoplasm,Unilateral Breast Cancers
D015412	Mastectomy, Segmental	Removal of only enough breast tissue to ensure that the margins of the resected surgical specimen are free of tumor.	Breast-Conserving Surgery,Lumpectomy,Partial Mastectomy,Breast Conservation Therapy,Breast Quadrantectomy,Breast-Sparing Surgery,Limited Resection Mastectomy,Local Excision Mastectomy,Segmentectomy,Surgery, Breast-Conserving,Breast Conservation Therapies,Breast Conserving Surgery,Breast Quadrantectomies,Breast Sparing Surgery,Breast-Conserving Surgeries,Breast-Sparing Surgeries,Conservation Therapies, Breast,Conservation Therapy, Breast,Limited Resection Mastectomies,Local Excision Mastectomies,Lumpectomies,Mastectomies, Limited Resection,Mastectomies, Local Excision,Mastectomies, Partial,Mastectomies, Segmental,Mastectomy, Limited Resection,Mastectomy, Local Excision,Mastectomy, Partial,Partial Mastectomies,Quadrantectomies, Breast,Quadrantectomy, Breast,Segmental Mastectomies,Segmental Mastectomy,Segmentectomies,Surgeries, Breast-Conserving,Surgeries, Breast-Sparing,Surgery, Breast Conserving,Surgery, Breast-Sparing
D062485	Breath Holding	An involuntary or voluntary pause in breathing, sometimes accompanied by loss of consciousness.	Breath Holdings,Holding, Breath,Holdings, Breath