Biomaterial Database

Host immunity against newborn Trichinella spiralis larvae of different ages. 1988

C H Wang, and R G Bell

James A. Baker Institute for Animal Health, Cornell University, Ithaca, New York 14853.

The infectivity of newborn Trichinella spiralis larvae of different ages was studied in normal rats. Newborn larvae collected after incubation of adult worms in vitro for 2, 12, or 24 hr were injected intravenously (i.v.) into normal AO rats in 3 separate recipient groups. All recipient rats developed strikingly similar numbers of muscle larvae 20 days later. The susceptibility to immunity by newborn larvae of different ages was also studied. No difference was found when degree of protection was compared by assessing muscle larvae burden or peritoneal anti-newborn larvae effects after injection of newborn larvae of different ages either i.v. or intraperitoneally into immunized recipient rats. We conclude that newborn larvae of any age up to 24 hr have similar infectivity in normal rats and are equally susceptible to anti-newborn larvae immunity in vivo.

UI	MeSH Term	Description	Entries
D007114	Immunization	Deliberate stimulation of the host's immune response. ACTIVE IMMUNIZATION involves administration of ANTIGENS or IMMUNOLOGIC ADJUVANTS. PASSIVE IMMUNIZATION involves administration of IMMUNE SERA or LYMPHOCYTES or their extracts (e.g., transfer factor, immune RNA) or transplantation of immunocompetent cell producing tissue (thymus or bone marrow).	Immunologic Stimulation,Immunostimulation,Sensitization, Immunologic,Variolation,Immunologic Sensitization,Immunological Stimulation,Sensitization, Immunological,Stimulation, Immunologic,Immunizations,Immunological Sensitization,Immunological Sensitizations,Immunological Stimulations,Sensitizations, Immunological,Stimulation, Immunological,Stimulations, Immunological,Variolations
D007814	Larva	Wormlike or grublike stage, following the egg in the life cycle of insects, worms, and other metamorphosing animals.	Maggots,Tadpoles,Larvae,Maggot,Tadpole
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D010529	Peritoneal Cavity	The space enclosed by the peritoneum. It is divided into two portions, the greater sac and the lesser sac or omental bursa, which lies behind the STOMACH. The two sacs are connected by the foramen of Winslow, or epiploic foramen.	Greater Sac,Lesser Sac,Omental Bursa,Bursa, Omental,Cavity, Peritoneal,Sac, Greater,Sac, Lesser
D000367	Age Factors	Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time.	Age Reporting,Age Factor,Factor, Age,Factors, Age
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014234	Trichinella	A genus of parasitic nematodes that causes TRICHINELLOSIS in man and other animal.	Trichina,Trichinas,Trichinellas
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus