Biomaterial Database

Effects of caffeine on simple reaction time and movement time. 1987

B H Jacobson, and B M Edgley

Oklahoma State University, Stillwater 74078-0616.

There were 19 males and 11 females with a mean age of 21 +/- 3 years and a mean weight of 72.8 +/- 3.2 kg who participated in an experiment to investigate the effect of caffeine on simple reaction time (RT) and movement time (MT). Subjects were randomly assigned to one of three groups--two experimental groups and one control group. Caffeine was administered using a double-blind format: Group 1, 600 mg caffeine; Group 2, 300 mg caffeine. Group 3, the control group, was given a placebo. All subjects were pre-tested for RT and MT prior to consumption of one of the three solutions. Post-test was conducted subsequent to an absorption period of 45 min. Results indicated a significant effect (p less than 0.05) between pre- and post-test measurements for both RT and MT favoring the 300 mg group. However, no significant effect (p greater than 0.05) was found between pre- and post-test measurements for RT or MT in the 600-mg group.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009068	Movement	The act, process, or result of passing from one place or position to another. It differs from LOCOMOTION in that locomotion is restricted to the passing of the whole body from one place to another, while movement encompasses both locomotion but also a change of the position of the whole body or any of its parts. Movement may be used with reference to humans, vertebrate and invertebrate animals, and microorganisms. Differentiate also from MOTOR ACTIVITY, movement associated with behavior.	Movements
D011930	Reaction Time	The time from the onset of a stimulus until a response is observed.	Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D002110	Caffeine	A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.	1,3,7-Trimethylxanthine,Caffedrine,Coffeinum N,Coffeinum Purrum,Dexitac,Durvitan,No Doz,Percoffedrinol N,Percutaféine,Quick-Pep,Vivarin,Quick Pep,QuickPep
D004305	Dose-Response Relationship, Drug	The relationship between the dose of an administered drug and the response of the organism to the drug.	Dose Response Relationship, Drug,Dose-Response Relationships, Drug,Drug Dose-Response Relationship,Drug Dose-Response Relationships,Relationship, Drug Dose-Response,Relationships, Drug Dose-Response
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults