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IgG4-related sclerosing cholangitis: not always an obvious entity. 2021
Magdalini Velegraki, and
Emmanouil Vardas, and
Christos Dervenis, and
Maria Fragaki, and
Pinelopi Nikolaou, and
Afroditi Mpitouli, and
George Kazamias, and
Athanasia Sepsa, and
Elpida Giannikaki, and
Gregorios A Paspatis
Department of Gastroenterology, Venizeleion General Hospital, Heraklion (Magdalini Velegraki, Emmanouil Vardas, Maria Fragaki, Pinelopi Nikolaou, Afroditi Mpitouli, Gregorios A. Paspatis).
Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is a distinct type of cholangitis, currently recognized as a biliary manifestation of IgG4-related disease. We present a case of type 3 IgG4-SC in a patient with normal IgG4 serum levels, surgically treated for suspicion of cholangiocarcinoma. This case highlights that differentiating between isolated IgG4-SC and cholangiocarcinoma can present a challenging diagnostic dilemma.
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