"Spot" urine collections do not accurately represent 24-hour sodium excretion in surgically stressed children. 1987

E G Ford, and L M Jennings, and R J Andrassy
Department of Surgery, University of Texas Health Science Center, Houston.

Deranged metabolism in posttraumatic or surgically stressed children makes fluid and electrolyte management difficult. Clear guidelines for salt and fluid administration have not been established. Recent management trends utilize four-hour and eight-hour "spot" urine collection measurement to imply 24-hour requirements. Six children, having suffered traumatic disease or surgical stress, were studied on an hourly basis for characterization of urinary sodium loss. Measured hourly values were combined to represent four-hour and eight-hour "spot" collections and then extrapolated to represent 24-hour losses. A great variation in sodium excretion was demonstrated on hourly samples; the variations were compounded by extrapolation. The extrapolated values varied from the measured hourly sodium losses by 0.66 to 123%. The four-hour extrapolations varied from measured values 14 to 198% (mean 55.2%). The eight-hour combinations varied 6.59 to 136% (mean 44.1%). On the basis of these data, we discourage the use of extrapolated values to imply 24-hour requirements. We support the use of a standard intravenous fluid (one-half strength normal saline or Ringer's lactate) with frequent urinary sodium determinations to individualize fluid and electrolyte management.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008297 Male Males
D009318 Natriuresis Sodium excretion by URINATION. Natriureses
D011184 Postoperative Period The period following a surgical operation. Period, Postoperative,Periods, Postoperative,Postoperative Periods
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D005440 Fluid Therapy Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS. Oral Rehydration Therapy,Rehydration,Rehydration, Oral,Oral Rehydration,Rehydration Therapy, Oral,Therapy, Fluid,Therapy, Oral Rehydration,Fluid Therapies,Oral Rehydration Therapies,Oral Rehydrations,Rehydration Therapies, Oral,Rehydrations,Rehydrations, Oral,Therapies, Fluid,Therapies, Oral Rehydration
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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