Transplantation of children's kidneys into adult recipients. 1978

S Boczko, and V Tellis, and F J Veith

In the present study of 31 kidneys transplanted from donors ranging in age from one to one-half to nine years, the ability of kidneys from donors in the pediatric age group to provide adequate renal function in adults is evaluated. Kidney function was reviewed six months, one year, three years and five years after transplantation. Forty per cent of the transplanted kidneys from this age group had excellent function at six months. Of the kidneys at risk for five years, 30 per cent were still functioning. Kidneys from donors three years of age and younger developed a creatinine clearance rate of 20 milliliters per minute in 12 days or less. Maximum creatinine clearance rates for kidneys from donors of the pediatric age group equaled those of adult donors. In addition, recipients of pediatric kidneys after one year tended to maintain a lower creatinine level than did their counterparts receiving adult kidneys. Thus, kidneys from donors as young as 18 months of age can be transplanted individually without special difficulties and can be expected to provide excellent renal function for adult recipients.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D006085 Graft Survival The survival of a graft in a host, the factors responsible for the survival and the changes occurring within the graft during growth in the host. Graft Survivals,Survival, Graft,Survivals, Graft
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age
D014019 Tissue Donors Individuals supplying living tissue, organs, cells, blood or blood components for transfer or transplantation to histocompatible recipients. Organ Donors,Donors,Ovum Donors,Semen Donors,Transplant Donors,Donor,Donor, Organ,Donor, Ovum,Donor, Semen,Donor, Tissue,Donor, Transplant,Donors, Organ,Donors, Ovum,Donors, Semen,Donors, Tissue,Donors, Transplant,Organ Donor,Ovum Donor,Semen Donor,Tissue Donor,Transplant Donor
D014184 Transplantation, Homologous Transplantation between individuals of the same species. Usually refers to genetically disparate individuals in contradistinction to isogeneic transplantation for genetically identical individuals. Transplantation, Allogeneic,Allogeneic Grafting,Allogeneic Transplantation,Allografting,Homografting,Homologous Transplantation,Grafting, Allogeneic

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