Biomaterial Database

Visual field defects, cup-disc ratio and fluorescein angiography in glaucomatous optic atrophy. 1978

S Tsukahara, and S Nagataki, and M Sugaya, and S Yoshida, and Y Komuro

Fluorescein angiography was carried out in 150 glaucoma subjects. Among them 94 subjects were selected to evaluate the correlation between functional loss and the findings of fluorescein angiography in the optic disc. The intensity of fluorescence was assessed in the superficial reticular capillaries and radial epipapillary capillaries. Functional loss was estimated by the visual field defects and cup-disc ratio. A marked decrease in the capillaries was seen in accordance with the increase in the cup-disc ratio. Also, the intensity of fluorescence in the optic disc paralleled the change in the visual field: the greater the deterioration in the visual field, the fewer the capillaries in the optic nerve head and vice versa. The fluorograms of 94 subjects were placed in one out of six groups, i.e. (1) normal, (2) arcuate scotoma, (3) superior or inferior nasal defects, (4) superior or inferior defects, (5) central residue or (6) temporal residue. The common factors correlating the fluorescein angiography in the glaucomatous optic disc with visual field loss were explored in 94 subjects, and it was possible to predict the visual field change from the capillary distribution in the glaucomatous optic disc.

UI	MeSH Term	Description	Entries
D009896	Optic Atrophy	Atrophy of the optic disk which may be congenital or acquired. This condition indicates a deficiency in the number of nerve fibers which arise in the RETINA and converge to form the OPTIC DISK; OPTIC NERVE; OPTIC CHIASM; and optic tracts. GLAUCOMA; ISCHEMIA; inflammation, a chronic elevation of intracranial pressure, toxins, optic nerve compression, and inherited conditions (see OPTIC ATROPHIES, HEREDITARY) are relatively common causes of this condition.	Atrophy, Optic
D009898	Optic Disk	The portion of the optic nerve seen in the fundus with the ophthalmoscope. It is formed by the meeting of all the retinal ganglion cell axons as they enter the optic nerve.	Blind Spot,Optic Disc,Optic Nerve Head,Optic Papilla,Blind Spots,Disc, Optic,Disk, Optic,Head, Optic Nerve,Nerve Head, Optic,Optic Discs,Optic Disks,Optic Nerve Heads,Optic Papillas,Papilla, Optic,Papillas, Optic,Spot, Blind
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D005451	Fluorescein Angiography	Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature.	Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D005901	Glaucoma	An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)	Glaucomas
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012607	Scotoma	A localized defect in the visual field bordered by an area of normal vision. This occurs with a variety of EYE DISEASES (e.g., RETINAL DISEASES and GLAUCOMA); OPTIC NERVE DISEASES, and other conditions.	Scotoma, Arcuate,Scotoma, Bjerrum,Scotoma, Central,Scotoma, Centrocecal,Scotoma, Altitudinal,Scotoma, Paracecal,Scotoma, Paracentral,Scotoma, Peripheral,Scotoma, Ring,Scotoma, Scintillating,Scotoma, Sector,Altitudinal Scotoma,Altitudinal Scotomas,Arcuate Scotoma,Arcuate Scotomas,Bjerrum Scotoma,Bjerrum Scotomas,Central Scotoma,Central Scotomas,Centrocecal Scotoma,Centrocecal Scotomas,Paracecal Scotoma,Paracecal Scotomas,Paracentral Scotoma,Paracentral Scotomas,Peripheral Scotoma,Peripheral Scotomas,Ring Scotoma,Ring Scotomas,Scintillating Scotoma,Scintillating Scotomas,Scotomas,Scotomas, Altitudinal,Scotomas, Arcuate,Scotomas, Bjerrum,Scotomas, Central,Scotomas, Centrocecal,Scotomas, Paracecal,Scotomas, Paracentral,Scotomas, Peripheral,Scotomas, Ring,Scotomas, Scintillating,Scotomas, Sector,Sector Scotoma,Sector Scotomas
D014794	Visual Fields	The total area or space visible in a person's peripheral vision with the eye looking straightforward.	Field, Visual,Fields, Visual,Visual Field