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The authors report a clinicopathologic study of 16 cases of bronchial carcinoid in 11 women and 5 men. Histologically, there were 15 cases of typical carcinoid and one case of atypical carcinoid. Typical carcinoids displayed endocrinoid pattern with regular cells. Atypical carcinoid had still recognizable endocrinoid pattern, but with increased cellular pleomorphism and mitotic activity. The argyrophilic stain and the immunohistochemical stain with a monoclonal antibody against cytokeratin were positive in all cases. Typical carcinoid were treated only by surgical resection. One case was treated by conservative bronchial resection and an other by tumoral enucleation. Thirteen were alive disease-free. The remaining patients have been lost to follow up. However atypical carcinoid received an adjuvant chemotherapy, but he died 4 months after pneumonectomy.
K B Romdhane, and
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M B Ayed
November 1984,
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