Solar retinopathy: its significance for the ageing eye and the younger pseudophakic patient. 1987

A B Hunyor

The sun is the main source of ultraviolet (UV), visible and infrared radiation reaching our atmosphere. The short wavelength components of the sun's spectrum have been shown to have deleterious effects on the retinal photoreceptors. These effects are photochemical and mostly not thermal in nature. Except in early life, most of the ultraviolet (300-400 nm) is effectively filtered out by the lens which in later life also filters out considerable proportions of shorter visible wavelengths to 450 nm. The photochemical effects are mediated by the production of free radicals from the interaction of oxygen, photons and receptor molecules. These radicals attack, among others, polyunsaturated fatty acid components of cell membranes which may eventually degenerate. Protective mechanisms within the receptors and the adjacent pigment epithelium may be overwhelmed in the presence of high retinal irradiances over prolonged periods of time--as may occur in aphakic and pseudophakic eyes. The cone system, with a much slower replacement rate of light-sensitive membranes, is more likely to suffer permanent damage than the rod system, with predictable consequences. The above considerations have special relevance in old patients because of their age-compromised retinas, and in the younger patient who may be rendered aphakic or pseudophakic and faces a prolonged period of exposure to excessive UV irradiation as a consequence. Protection for the retina, whether by sunglasses or UV-absorbing intraocular lenses, as appropriate, is recommended.

UI MeSH Term Description Entries
D012164 Retinal Diseases Diseases involving the RETINA. Disease, Retinal,Diseases, Retinal,Retinal Disease
D002386 Cataract Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed) Cataract, Membranous,Lens Opacities,Pseudoaphakia,Cataracts,Cataracts, Membranous,Lens Opacity,Membranous Cataract,Membranous Cataracts,Opacities, Lens,Opacity, Lens,Pseudoaphakias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging
D001035 Aphakia Absence of crystalline lens totally or partially from field of vision, from any cause except after cataract extraction. Aphakia is mainly congenital or as result of LENS DISLOCATION AND SUBLUXATION. Aphakic Eye,Aphakic Eye, Post-traumatic,Aphakic Eye, Traumatic,Aphakias,Aphakic Eye, Post traumatic,Aphakic Eyes,Aphakic Eyes, Post-traumatic,Eye, Aphakic,Eye, Traumatic Aphakic,Post-traumatic Aphakic Eye,Post-traumatic Aphakic Eyes,Traumatic Aphakic Eye,Traumatic Aphakic Eyes
D013472 Sunlight Irradiation directly from the sun. Sunshine

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