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Twelve patients with chronic renal failure who exhibited a progressive decline in 24-h creatinine clearance despite being given, for 2-10 months, a diet containing 0.3 g of protein/kg ideal weight and 7-9 mg of phosphorus/kg ideal weight supplemented with vitamins, CaCO3, and 10 g per day of essential amino acids, were changed to a supplement containing predominantly keto acids. In 6 patients whose serum creatinine levels were 7.5 mg/dl or greater at changeover, progression continued unabated. In 6 patients with serum creatinine levels at changeover of 6.5-7.4 mg/dl, one was non-compliant with the diet and progressed to dialysis. In the other 5, progression, measured as the rate of change of a bimonthly radioisotope clearance, has been undetectable during the ensuing 1-2 years.
M Walser, and
N LaFrance, and
L Ward, and
M A VanDuyn
January 1988,
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M A VanDuyn
January 1988,
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M Walser, and
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M A VanDuyn
June 1978,
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M A VanDuyn
March 2000,
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M Walser, and
N LaFrance, and
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M A VanDuyn
January 1986,
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M Walser, and
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M A VanDuyn
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M Walser, and
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M A VanDuyn
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