BIOMAT Database Logo BIOMAT Database Logo

Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection. 1987

R P Koshakji, and A J Wood
Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232.

UI MeSH Term Description Entries
D007202 Indicators and Reagents Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499) Indicator,Reagent,Reagents,Indicators,Reagents and Indicators
D011433 Propranolol A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs. Dexpropranolol,AY-20694,Anaprilin,Anapriline,Avlocardyl,Betadren,Dociton,Inderal,Obsidan,Obzidan,Propanolol,Propranolol Hydrochloride,Rexigen,AY 20694,AY20694,Hydrochloride, Propranolol
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D004355 Drug Stability The chemical and physical integrity of a pharmaceutical product. Drug Shelf Life,Drugs Shelf Lives,Shelf Life, Drugs,Drug Stabilities,Drugs Shelf Life,Drugs Shelf Live,Life, Drugs Shelf,Shelf Life, Drug,Shelf Live, Drugs,Shelf Lives, Drugs
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000432 Methanol A colorless, flammable liquid used in the manufacture of FORMALDEHYDE and ACETIC ACID, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness. Alcohol, Methyl,Carbinol,Sodium Methoxide,Wood Alcohol,Alcohol, Wood,Methoxide, Sodium,Methyl Alcohol
D000975 Antioxidants Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. Anti-Oxidant,Antioxidant,Antioxidant Activity,Endogenous Antioxidant,Endogenous Antioxidants,Anti-Oxidant Effect,Anti-Oxidant Effects,Anti-Oxidants,Antioxidant Effect,Antioxidant Effects,Activity, Antioxidant,Anti Oxidant,Anti Oxidant Effect,Anti Oxidant Effects,Anti Oxidants,Antioxidant, Endogenous,Antioxidants, Endogenous
D013050 Spectrometry, Fluorescence Measurement of the intensity and quality of fluorescence. Fluorescence Spectrophotometry,Fluorescence Spectroscopy,Spectrofluorometry,Fluorescence Spectrometry,Spectrophotometry, Fluorescence,Spectroscopy, Fluorescence

Related Publications

R P Koshakji, and A J Wood
High-performance liquid chromatographic determination of propranolol and 4-hydroxypropranolol in plasma.
June 1981, Journal of pharmaceutical sciences,
R P Koshakji, and A J Wood
High-performance liquid chromatographic determination of propranolol and 4-hydroxypropranolol in serum.
June 1988, Journal of clinical pharmacy and therapeutics,
R P Koshakji, and A J Wood
High-pressure liquid chromatographic method for the simultaneous quantitative analysis of propranolol and 4-hydroxypropranolol in plasma.
May 1978, Journal of chromatography,
R P Koshakji, and A J Wood
An improved extraction procedure for the liquid chromatographic determination of propranolol and 4-hydroxypropranolol in plasma.
October 1980, British journal of clinical pharmacology,
R P Koshakji, and A J Wood
Improved liquid-chromatographic determination of propranolol in plasma, with fluorescence detection.
May 1979, Clinical chemistry,
R P Koshakji, and A J Wood
High-performance liquid chromatographic assay for the derivatized enantiomers of propranolol and 4-hydroxypropranolol in human plasma.
January 1991, Journal of pharmaceutical and biomedical analysis,
R P Koshakji, and A J Wood
Determination of propranolol and 4-hydroxypropranolol in human plasma by high-performance liquid chromatography.
October 1989, The Analyst,
R P Koshakji, and A J Wood
Rapid high-performance liquid chromatographic method for the determination of propranolol in plasma.
April 1987, The Analyst,
R P Koshakji, and A J Wood
High performance liquid chromatographic method for the determination of sumatriptan with fluorescence detection in human plasma.
July 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences,
R P Koshakji, and A J Wood
Silica gel high-performance liquid chromatography for the simultaneous determination of propranolol and 4-hydroxypropranolol enantiomers after chiral derivatization.
October 1984, Journal of chromatography,
Copied contents to your clipboard!