Biomaterial Database

Renal function in patients undergoing major surgery under moderate normovolemic hemodilution. 1987

R Vara-Thorbeck, and J A Guerrero Fernandez Marcote

Faculdad de Medicina, Catedra de Patologia y Clinica Quirurgica II, Universidad de Granada.

A prospective randomized study on 100 patients with cholelithiasis, who were scheduled for cholecystectomy was carried out. 50 patients were hemodiluted (Hctr. 29-27%). In both groups, hemodiluted and non-hemodiluted patients, the following parameters were studied: renal function as regards glomerular filtration (creatine clearance, etc.) and also with reference to the concentrative capacity of the kidneys (free water and osmolar clearances). The results obtained show that M.N.H. significantly improves renal function. From the practical point of view we can conclude that the improved "performance" of the kidney in hemodiluted patients minimizes the nephrotoxis effects of many drugs and anaesthetic agents.

UI	MeSH Term	Description	Entries
D007677	Kidney Function Tests	Laboratory tests used to evaluate how well the kidneys are working through examination of blood and urine.	Function Test, Kidney,Function Tests, Kidney,Kidney Function Test,Test, Kidney Function,Tests, Kidney Function
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D001810	Blood Volume	Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.	Blood Volumes,Volume, Blood,Volumes, Blood
D002763	Cholecystectomy	Surgical removal of the GALLBLADDER.	Cholecystectomies
D002769	Cholelithiasis	Presence or formation of GALLSTONES in the BILIARY TRACT, usually in the gallbladder (CHOLECYSTOLITHIASIS) or the common bile duct (CHOLEDOCHOLITHIASIS).	Gallstone Disease,Cholelithiases,Gallstone Diseases
D006438	Hemodilution	Reduction of blood viscosity usually by the addition of cell free solutions. Used clinically (1) in states of impaired microcirculation, (2) for replacement of intraoperative blood loss without homologous blood transfusion, and (3) in cardiopulmonary bypass and hypothermia.	Hemodilutions
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014882	Water-Electrolyte Balance	The balance of fluid in the BODY FLUID COMPARTMENTS; total BODY WATER; BLOOD VOLUME; EXTRACELLULAR SPACE; INTRACELLULAR SPACE, maintained by processes in the body that regulate the intake and excretion of WATER and ELECTROLYTES, particularly SODIUM and POTASSIUM.	Fluid Balance,Electrolyte Balance,Balance, Electrolyte,Balance, Fluid,Balance, Water-Electrolyte,Water Electrolyte Balance