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Impairments of protein metabolism, expressed as predominance of catabolism over anabolism and hypoproteinemia, were observed in one month old rats with experimental burns of the IIIA-IIIB degree, when 20-25% of a body surface was impaired. After administration of steroid drugs (retabolyl at a dose of 1 mg/100 g of body mass or oxymetacyl--4-methyl-5-oxyuracil---at a dose of 5 mg/100 g of body mass) content of protein and urea normalized in blood serum, activity of cathepsin D decreased in tissues, the rate of 35S-methionine incorporation into tissue proteins increased. The pyrimidine derivative oxymetacyl exhibited higher effect on protein metabolism in burns of preadolescent rats as compared with retabolyl.
E G Davletov, and
R M Saliakhova, and
F Kh Kamilov
July 1969,
Kardiologiia,
E G Davletov, and
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F Kh Kamilov
January 1972,
Ukrains'kyi biokhimichnyi zhurnal,
E G Davletov, and
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E G Davletov, and
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F Kh Kamilov
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E G Davletov, and
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F Kh Kamilov
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Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
E G Davletov, and
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F Kh Kamilov
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Zhonghua wai ke za zhi [Chinese journal of surgery],
E G Davletov, and
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March 1949,
Quarterly journal of experimental physiology (Cambridge, England),
E G Davletov, and
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F Kh Kamilov
February 1975,
Vestnik khirurgii imeni I. I. Grekova,
