Biomaterial Database

In vitro release characteristics of diclofenac and hydrocortisone from Pluronic F-127 gels. 1987

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

UI	MeSH Term	Description	Entries
D009823	Ointment Bases	Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients.	Bases, Ointment
D011060	Poloxalene	A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.	Oxyethylene Oxypropylene Polymer,Polyoxyethylene Polyoxypropylene Polyoxyethylene Polymer,Bloat Guard,Poloxalene 2930,Proxanol,SK&F-18667,Tergitol,Therabloat,Oxypropylene Polymer, Oxyethylene,Polymer, Oxyethylene Oxypropylene,SK&F 18667,SK&F18667
D011092	Polyethylene Glycols	Polymers of ETHYLENE OXIDE and water, and their ethers. They vary in consistency from liquid to solid depending on the molecular weight indicated by a number following the name. They are used as SURFACTANTS, dispersing agents, solvents, ointment and suppository bases, vehicles, and tablet excipients. Some specific groups are NONOXYNOLS, OCTOXYNOLS, and POLOXAMERS.	Macrogols,Polyoxyethylenes,Carbowax,Macrogol,Polyethylene Glycol,Polyethylene Oxide,Polyethyleneoxide,Polyglycol,Glycol, Polyethylene,Glycols, Polyethylene,Oxide, Polyethylene,Oxides, Polyethylene,Polyethylene Oxides,Polyethyleneoxides,Polyglycols,Polyoxyethylene
D002626	Chemistry, Pharmaceutical	Chemistry dealing with the composition and preparation of agents having PHARMACOLOGIC ACTIONS or diagnostic use.	Medicinal Chemistry,Chemistry, Pharmaceutic,Pharmaceutic Chemistry,Pharmaceutical Chemistry,Chemistry, Medicinal
D004008	Diclofenac	A non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.	Diclophenac,Dichlofenal,Diclofenac Potassium,Diclofenac Sodium,Diclonate P,Dicrofenac,Feloran,GP-45,840,Novapirina,Orthofen,Orthophen,Ortofen,SR-38,Sodium Diclofenac,Voltaren,Voltarol,Diclofenac, Sodium,GP 45,840,GP45,840,SR 38,SR38
D005782	Gels	Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.
D006854	Hydrocortisone	The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.	Cortef,Cortisol,Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11beta)-,11-Epicortisol,Cortifair,Cortril,Epicortisol,Hydrocortisone, (11 alpha)-Isomer,Hydrocortisone, (9 beta,10 alpha,11 alpha)-Isomer,11 Epicortisol

Related Publications

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Comparison of lidocaine release from Pluronic F-127 gels and other formulations.

January 1981, Acta pharmaceutica Suecica,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Hydrolysis of indomethacin in Pluronic F-127 gels.

January 1988, Acta pharmaceutica Suecica,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Development and in vitro evaluation of insulin-loaded buccal Pluronic F-127 gels.

January 2010, Pharmaceutical development and technology,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Rheological, mucoadhesive and release properties of pluronic F-127 gel and pluronic F-127/polycarbophil mixed gel systems.

July 2005, Die Pharmazie,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Absorption of insulin from pluronic F-127 gels following subcutaneous administration in rats.

July 1999, International journal of pharmaceutics,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Applications of thermo-reversible pluronic F-127 gels in pharmaceutical formulations.

January 2006, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Tetrazolium salts-Pluronic F-127 gels for 3D radiotherapy dosimetry.

May 2018, Physics in medicine and biology,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Pluronic F-127 gels as a novel vehicle for rectal administration of indomethacin.

April 1986, Chemical & pharmaceutical bulletin,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Pluronic F-127 gels as a vehicle for topical administration of anticancer agents.

October 1984, Chemical & pharmaceutical bulletin,

H Tomida, and M Shinohara, and N Kuwada, and S Kiryu

Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels.

October 2002, Die Pharmazie,