Biomaterial Database

[Effects of oxygen free radicals and lipid peroxidation on the pathogenesis of ARDS]. 1987

L Li, and P S Li

UI	MeSH Term	Description	Entries
D008054	Lipid Peroxides	Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin E, structural separation or low oxygen tension.	Fatty Acid Hydroperoxide,Lipid Peroxide,Lipoperoxide,Fatty Acid Hydroperoxides,Lipid Hydroperoxide,Lipoperoxides,Acid Hydroperoxide, Fatty,Acid Hydroperoxides, Fatty,Hydroperoxide, Fatty Acid,Hydroperoxide, Lipid,Hydroperoxides, Fatty Acid,Peroxide, Lipid,Peroxides, Lipid
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D012128	Respiratory Distress Syndrome	A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA.	ARDS, Human,Acute Respiratory Distress Syndrome,Adult Respiratory Distress Syndrome,Pediatric Respiratory Distress Syndrome,Respiratory Distress Syndrome, Acute,Respiratory Distress Syndrome, Adult,Respiratory Distress Syndrome, Pediatric,Shock Lung,Distress Syndrome, Respiratory,Distress Syndromes, Respiratory,Human ARDS,Lung, Shock,Respiratory Distress Syndromes,Syndrome, Respiratory Distress
D005609	Free Radicals	Highly reactive molecules with an unsatisfied electron valence pair. Free radicals are produced in both normal and pathological processes. Free radicals include reactive oxygen and nitrogen species (RONS). They are proven or suspected agents of tissue damage in a wide variety of circumstances including radiation, damage from environment chemicals, and aging. Natural and pharmacological prevention of free radical damage is being actively investigated.	Free Radical
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013482	Superoxide Dismutase	An oxidoreductase that catalyzes the reaction between SUPEROXIDES and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide.	Hemocuprein,Ag-Zn Superoxide Dismutase,Cobalt Superoxide Dismutase,Cu-Superoxide Dismutase,Erythrocuprein,Fe-Superoxide Dismutase,Fe-Zn Superoxide Dismutase,Iron Superoxide Dismutase,Manganese Superoxide Dismutase,Mn-SOD,Mn-Superoxide Dismutase,Ag Zn Superoxide Dismutase,Cu Superoxide Dismutase,Dismutase, Ag-Zn Superoxide,Dismutase, Cobalt Superoxide,Dismutase, Cu-Superoxide,Dismutase, Fe-Superoxide,Dismutase, Fe-Zn Superoxide,Dismutase, Iron Superoxide,Dismutase, Manganese Superoxide,Dismutase, Mn-Superoxide,Dismutase, Superoxide,Fe Superoxide Dismutase,Fe Zn Superoxide Dismutase,Mn SOD,Mn Superoxide Dismutase,Superoxide Dismutase, Ag-Zn,Superoxide Dismutase, Cobalt,Superoxide Dismutase, Fe-Zn,Superoxide Dismutase, Iron,Superoxide Dismutase, Manganese
D014810	Vitamin E	A generic descriptor for all TOCOPHEROLS and TOCOTRIENOLS that exhibit ALPHA-TOCOPHEROL activity. By virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus, these compounds exhibit varying degree of antioxidant activity, depending on the site and number of methyl groups and the type of ISOPRENOIDS.
D024502	alpha-Tocopherol	A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.	3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol,R,R,R-alpha-Tocopherol,Tocopherol Acetate,Tocopherol Succinate,Tocopheryl Acetate,Vitamin E Succinate,alpha-Tocopherol Acetate,alpha-Tocopherol Hemisuccinate,alpha-Tocopherol Succinate,alpha-Tocopheryl Calcium Succinate,d-alpha Tocopherol,d-alpha-Tocopheryl Acetate,Acetate, Tocopherol,Tocopherol, d-alpha,alpha Tocopherol,alpha Tocopherol Acetate,alpha Tocopherol Hemisuccinate,alpha Tocopherol Succinate,alpha Tocopheryl Calcium Succinate,d alpha Tocopherol,d alpha Tocopheryl Acetate
D024505	Tocopherols	A collective name for a group of closely related lipids that contain substitutions on the 2H-1-benzopyran-6-ol nucleus and a long hydrocarbon chain of isoprenoid units. They are antioxidants by virtue of the phenolic hydrogen. Tocopherols react with the most reactive form of oxygen and protect unsaturated fatty acids from oxidation.	Tocopherol,Abortosan,Antioxidans E-Hevert,Aquasol E,Auxina E,Bio E,Biopto-E,Biosan,Bioweyxin,Dal-E,Davitamon,Dermorelle,Detulin,E Vitamin E,E-Mulsin,E-Vicotrat,E-Vitamin-Ratiopharm,E-ferol,EUNOVA Vitamin E,Ecoro,Elex Verla,Embial,Ephynal,Eplonat,Equivit E,Eusovit,Evion,Hydrovit E,Lasar,Malton E,Micorvit E,Mowivit Vitamin E,Puncto E,Richtavit E,Sanavitan S,Snow-E Muscle, Energy & Feritility,Spondyvit,Tocolion,Tocopa,Tocopharm,Tocopherol Bayer,Tocovital,Togasan Vitamin E,Unique E,Uno-Vit,Vibolex,Vit E hydrosol,Vit. E Stada,Vita-E,Vita-Plus E,Vitagutt Vitamin E,Vitamin E AL,Vitamin E Natur,Vitamin E Sanum,Vitamin E Suspension,Vitamin E-mp,Vitamin-E Dragees,Vitamin-E EVI-MIRALE,Vitamine E GNR,Vitazell,Dal E,E Mulsin,E Vicotrat,Uno Vit,UnoVit,Vita E,Vita Plus E,VitaE,VitaPlus E,Vitamin E Dragees,Vitamin E EVI MIRALE,Vitamin E mp,Vitamin E, Mowivit,Vitamin E, Togasan,Vitamin E, Vitagutt,Vitamin Emp,VitaminE EVIMIRALE