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SHBG, testosterone, androstenedione, 17-OH-Progesterone plasma levels in PCO affected women treated with a triphasic oral contraceptive. 1987
P Negri, and
G Agnello, and
F Borghesani, and
L Tomain, and
N Minisci, and
G D'Errico, and
A R Cavallini
Istituto di Clinica Ostetrica e Ginecologica dell'Università degli Studi di Ferrara.
A triphasic oral contraceptive Trigynon (Schering) or Triphasil (Wyeth) was administered to 13 anovulatory women with hyperandrogenism, enlarged polycystic ovaries and reversal of LH/FSH ratio. After three months of treatment total Testosterone, Androstenedione and 17-OH-Progesterone levels significantly decreased while SHBG significantly increased. Reduction of hair growth and improvement of acne were noted. Side effects were minimal.
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